A0A1E1XNU8 · A0A1E1XNU8_AMBSC

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionadenylate cyclase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Biological Processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological ProcesscAMP biosynthetic process
Biological Processintracellular signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    adenylate cyclase
  • EC number

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Amblyomminae > Amblyomma

Accessions

  • Primary accession
    A0A1E1XNU8

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane26-45Helical
Transmembrane66-83Helical
Transmembrane117-135Helical
Transmembrane179-197Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-16
ChainPRO_500911620617-574adenylate cyclase

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain261-398Guanylate cyclase
Compositional bias445-507Polar residues
Region445-574Disordered
Compositional bias525-550Polar residues

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    574
  • Mass (Da)
    64,511
  • Last updated
    2017-01-18 v1
  • Checksum
    73625446C44A3B09
MTCAFITWIFIIICQAVMLPKSLFMTVSYSVVSSLLAIILLAAVGSECRWSPASLVKASKLLEEQCFWRNIVICSTILLMYIASTGTMFVCDRQSSNSTIQCRQEPSESPLCCYPQYYVFSWMLYMVACSAFIKLNYLIKVAMLTAMALTDILLVKVFFPDVFRRSHKGYDVILSVEDRMPILIAVFFYIVVYHCRLTEVTSRLDFLWKRQAQTNLQSMREICSYNTQLLRNVLPDHVATYFLTHDRKNEELYAQSYVCCGVMFASIPNFANFYSEDINNGVECIRLLNEIIFDFDQLLDDERFQCLEKIKTISSTYMAASGLNPKDQNLASWVHLTALVDFAISMKEALEDVNKHSFNNFKLRVGISHGPLVGGVIGARKPVYDIWGNTVNVASRMDSTGLPNHTQVTEEVYQLLRDGPYVFQCRGKVKVKGKGEMTTYFLVDRKSNRSASSPREEGVSGGQPGSVSRQEDNSPSGALSPPFSSDSLQLRRESGHTPNSWTGQQPKAASLMPPHDDVLPYTQPKPIIVSNTPPHGSRSRVKTGVSSKPESLTRGDPWESLKQIRVPPPSLPGD

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias445-507Polar residues
Compositional bias525-550Polar residues
Non-terminal residue574

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GFAA01002499
EMBL· GenBank· DDBJ
JAU00936.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp