A0A1E1UVS4 · A0A1E1UVS4_9HYPH
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids718 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 469 | Determinant of potassium independence | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Boseaceae > Bosea
Accessions
- Primary accessionA0A1E1UVS4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-25 | Helical | ||||
Sequence: IIIVLSALSIAYGIWAYGDV | ||||||
Transmembrane | 54-72 | Helical | ||||
Sequence: YATISVVGAALFVVLTYLL | ||||||
Transmembrane | 78-99 | Helical | ||||
Sequence: IGFLIGAILSGAAGFIGMNVSV | ||||||
Transmembrane | 119-146 | Helical | ||||
Sequence: VAFKAGAVTGMLVAGLALLGVAVYYGVL | ||||||
Transmembrane | 158-177 | Helical | ||||
Sequence: TVIDSLVALGFGASLISIFA | ||||||
Transmembrane | 235-255 | Helical | ||||
Sequence: YAVTLVATMVLSAIFFAGQPV | ||||||
Transmembrane | 261-281 | Helical | ||||
Sequence: LYPMAIGAACIVTSILGTFFV | ||||||
Transmembrane | 293-314 | Helical | ||||
Sequence: LYKGFIAAGVLSVGAIAAVNWL | ||||||
Transmembrane | 334-353 | Helical | ||||
Sequence: ANLFGCALVGLAVTLFIVVI | ||||||
Transmembrane | 396-429 | Helical | ||||
Sequence: IVIIAGIIVSYTLAGLFGIAIATTAMLALAGVVV | ||||||
Transmembrane | 475-499 | Helical | ||||
Sequence: YAIGSAGLGALVLFAAYTSDLNFFI | ||||||
Transmembrane | 520-541 | Helical | ||||
Sequence: FTLSNPFVVVGLLLGGLIPFLF | ||||||
Transmembrane | 594-615 | Helical | ||||
Sequence: MIVPSLLPVLAPIVTFFAINAI | ||||||
Transmembrane | 622-641 | Helical | ||||
Sequence: FAAVGAMLMGVIVTGIFVAI | ||||||
Transmembrane | 696-716 | Helical | ||||
Sequence: AVNPAIKITNIIALLLLAILA |
Keywords
- Cellular component
Interaction
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length718
- Mass (Da)73,316
- Last updated2017-01-18 v1
- Checksum97BDA0DA95B40CD5