A0A1D8PL68 · RL40B_CANAL

Function

function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site.

1525101520253035404550MIEPSLKALASKYNCEKSICRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
TypeIDPosition(s)Description
Binding site20Zn2+ 101 (UniProtKB | ChEBI)
Binding site23Zn2+ 101 (UniProtKB | ChEBI)
Binding site34Zn2+ 101 (UniProtKB | ChEBI)
Binding site39Zn2+ 101 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentribonucleoprotein complex
Cellular Componentribosome
Molecular Functionstructural constituent of ribosome
Biological Processtranslation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Large ribosomal subunit protein eL40
  • Alternative names
    • 60S ribosomal protein L40-B

Gene names

    • Name
      RPL40B
    • ORF names
      CAALFM_C401050CA
    • Ordered locus names
      orf19.4684.2

Organism names

Accessions

  • Primary accession
    A0A1D8PL68

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004565001-52Large ribosomal subunit protein eL40

Interaction

Subunit

Component of the large ribosomal subunit (PubMed:35613268).
Mature ribosomes consist of a small (40S) and a large (60S) subunit (PubMed:35613268).
The 40S subunit contains about 32 different proteins and 1 molecule of RNA (18S) (PubMed:35613268).
The 60S subunit contains 45 different proteins and 3 molecules of RNA (25S, 5.8S and 5S) (PubMed:35613268).

Protein-protein interaction databases

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    52
  • Mass (Da)
    6,061
  • Last updated
    2017-01-18 v1
  • MD5 Checksum
    4095F213AF09A7FF0D63383A277CFF25
MIEPSLKALASKYNCEKSICRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017626
EMBL· GenBank· DDBJ
AOW28892.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help