A0A1D8MSJ1 · A0A1D8MSJ1_9EURY

Function

function

Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site225pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site267-270pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site270substrate
Binding site306substrate
Active site337Proton donor
Binding site366pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site366substrate

GO annotations

AspectTerm
Molecular Functiondiaminopimelate decarboxylase activity
Molecular Functionpyridoxal phosphate binding
Biological Processlysine biosynthetic process via diaminopimelate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diaminopimelate decarboxylase
  • EC number
  • Short names
    DAP decarboxylase
    ; DAPDC

Gene names

    • Name
      lysA
    • ORF names
      AQV86_03340

Organism names

Accessions

  • Primary accession
    A0A1D8MSJ1

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue56N6-(pyridoxal phosphate)lysine

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain31-274Orn/DAP/Arg decarboxylase 2 N-terminal
Domain275-364Orn/DAP/Arg decarboxylase 2 C-terminal

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    410
  • Mass (Da)
    45,696
  • Last updated
    2017-01-18 v1
  • Checksum
    1729D7059AFDD1C1
MNEKLEIGGLAAEEIVEDHGTPLFVYDAERIRDQYRKLDDAFSSRYDDFMINFAVKSNFNPIIARLLVEEGAGLDCASKAEILLANEIGADEVMYTAPYNRKDEIEYAIEHGATVNLDSIFLPEKIDEMPEEICFRIDPGIGEGDHGLVFGGGDTKFGIPEERAVEAYRKAKERGAEKFGIHMMTGSNVRNPEYFGQITEKLLEIAGEIAEELDIEFEFVDVGGGLGVPYRPGDEELDIERTGENIIEKFQEGIEKYDIGRPQLRIEPGRYLVAQSGYLLSRVTGVKKKVGTEFVGIDTGMHHNLRPMLLDAYHEIRLAEDVEKPVDGKKTVVGPVCSSIDVMAEDRELPEMSEGDLVSIEDVGAYGFTMASHWNSRPLPAEVLVDDGEAEVIRKREGLRDVFHGTGLEK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP012986
EMBL· GenBank· DDBJ
AOV94934.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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