A0A1D6K6U5 · CPPS2_MAIZE
- ProteinEnt-copalyl diphosphate synthase 2, chloroplastic
- GeneCPPS2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids825 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Involved in gibberellin biosynthesis (PubMed:16307364).
Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate (ent-CPP) (PubMed:16307364).
Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed:29475898).
In response to fungal infection and in associtation with KSL4, is involved in the production dolabradiene, a type of antifungal phytoalexin (PubMed:29475898).
Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate (ent-CPP) (PubMed:16307364).
Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed:29475898).
In response to fungal infection and in associtation with KSL4, is involved in the production dolabradiene, a type of antifungal phytoalexin (PubMed:29475898).
Catalytic activity
- (2E,6E,10E)-geranylgeranyl diphosphate = ent-copalyl diphosphateThis reaction proceeds in the forward direction.
Cofactor
Pathway
Plant hormone biosynthesis; gibberellin biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 241 | substrate | ||||
Sequence: K | ||||||
Binding site | 459 | substrate | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Molecular Function | ent-copalyl diphosphate synthase activity | |
Molecular Function | isomerase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | terpene synthase activity | |
Biological Process | defense response | |
Biological Process | diterpene phytoalexin biosynthetic process | |
Biological Process | diterpenoid biosynthetic process | |
Biological Process | gibberellin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEnt-copalyl diphosphate synthase 2, chloroplastic
- EC number
- Short namesEnt-CPP synthase 2 ; Ent-CPS 2
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea
Accessions
- Primary accessionA0A1D6K6U5
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-70 | Chloroplast | ||||
Sequence: MVLSSSCTTVPHLSSLAVVQLGPWSSRIKKKTDAVAVPAAAGRWRARARAQDTSESAAVAKGSSLTPIVR | ||||||
Chain | PRO_0000447770 | 71-825 | Ent-copalyl diphosphate synthase 2, chloroplastic | |||
Sequence: TDAESRRTRWPTDDDDAEPLVDEIRAMLTSMSDGDISVSAYDTAWVGLVPRLDGGEGPQFPAAVRWIRNNQLPDGSWGDAALFSAYDRLINTLACVVTLTRWSLEPEMRGRGLSFLGRNMWKLATEDEESMPIGFELAFPSLIELAKSLGVHDFPYDHQALQAIYSSREIKVKRIPKEVMHTVPTSILHSLEGMPGLDWARLLKLQSSDGSFLFSPAATAYALMNTGDDRCFSYIDRTVKKFNGGVPNVYPVDLFEHIWAVDRLERLGISRYFQKEIEQCMDYVNRHWTEDGICWARNSDVKEVDDTAMAFRLLRLHGYSVSPDVFKNFEKDGEFFAFVGQSNQAVTGMYNLNRASQISFPGEDVLHRAGPFSYEFLRRKQAEGALRDKWIISKDLPGEVVYTLDFPWYGNLPRVEARDYLEQYGGGDDVWIGKTLYRMPLVNNDVYLELARMDFNHCQALHQLEWQGLKKWYTENRLMDFGVAQEDALRAYFLAAASVYEPCRAAERLAWARAAILANAVSTHLRNSPSFRERLEHSLRCRPSEETDGSWFNSSSGSDAVLVKAVLRLTDSLAREAQPIHGGDPEDIHKLLRSAWAEWVREKADAADSVCNGSSAVEQEGSRMVHDKQTCLLLARMIEISAGRAAGEAASEDGDRRIIQLTGSICDSLKQKMLVSQDPEKNEEMMSHVDDELKLRIREFVQYLLRLGEKKTGSSETRQTFLSIVKSCYYAAHCPPHVVDRHISRVIFEPVSAAK |
Proteomic databases
Expression
Tissue specificity
Expressed in tassels.
Induction
Induced by the fungal pathogens Fusarium graminearum and Fusarium verticillioides.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 373-376 | DXDD motif | ||||
Sequence: EVDD |
Domain
The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity through binding to Mg2+.
Sequence similarities
Belongs to the terpene synthase family. Tpsc subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length825
- Mass (Da)92,762
- Last updated2019-09-18 v2
- Checksum1004925ED2C9A152
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 34 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: A → T | ||||||
Sequence conflict | 45 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: R → RR | ||||||
Sequence conflict | 47 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: R → L | ||||||
Sequence conflict | 52 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: D → H | ||||||
Sequence conflict | 233 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: A → G | ||||||
Sequence conflict | 242 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: V → M | ||||||
Sequence conflict | 271 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: R → K | ||||||
Sequence conflict | 441 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: P → A | ||||||
Sequence conflict | 451 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: Q → E | ||||||
Sequence conflict | 541 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: K → R | ||||||
Sequence conflict | 657 | in Ref. 1; AAT70083/AAT70084 | ||||
Sequence: D → DI |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY562490 EMBL· GenBank· DDBJ | AAT70083.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY562491 EMBL· GenBank· DDBJ | AAT70084.1 EMBL· GenBank· DDBJ | mRNA | ||
CM007647 EMBL· GenBank· DDBJ | ONL99283.1 EMBL· GenBank· DDBJ | Genomic DNA |