A0A1D6K6U5 · CPPS2_MAIZE

  • Protein
    Ent-copalyl diphosphate synthase 2, chloroplastic
  • Gene
    CPPS2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

Involved in gibberellin biosynthesis (PubMed:16307364).
Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate (ent-CPP) (PubMed:16307364).
Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed:29475898).
In response to fungal infection and in associtation with KSL4, is involved in the production dolabradiene, a type of antifungal phytoalexin (PubMed:29475898).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Plant hormone biosynthesis; gibberellin biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site241substrate
Binding site459substrate

GO annotations

AspectTerm
Cellular Componentchloroplast
Molecular Functionent-copalyl diphosphate synthase activity
Molecular Functionisomerase activity
Molecular Functionmagnesium ion binding
Molecular Functionterpene synthase activity
Biological Processdefense response
Biological Processditerpene phytoalexin biosynthetic process
Biological Processditerpenoid biosynthetic process
Biological Processgibberellin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ent-copalyl diphosphate synthase 2, chloroplastic
  • EC number
  • Short names
    Ent-CPP synthase 2
    ; Ent-CPS 2
  • Alternative names
    • Protein ANTHER EAR 2
      (ZmAN2
      )

Gene names

    • Name
      CPPS2
    • Synonyms
      AN2
    • ORF names
      ZEAMMB73_Zm00001d029648

Organism names

  • Taxonomic identifier
  • Strain
    • cv. B73
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea

Accessions

  • Primary accession
    A0A1D6K6U5
  • Secondary accessions
    • Q672R4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-70Chloroplast
ChainPRO_000044777071-825Ent-copalyl diphosphate synthase 2, chloroplastic

Proteomic databases

Expression

Tissue specificity

Expressed in tassels.

Induction

Induced by the fungal pathogens Fusarium graminearum and Fusarium verticillioides.

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif373-376DXDD motif

Domain

The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity through binding to Mg2+.

Sequence similarities

Belongs to the terpene synthase family. Tpsc subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    825
  • Mass (Da)
    92,762
  • Last updated
    2019-09-18 v2
  • Checksum
    1004925ED2C9A152
MVLSSSCTTVPHLSSLAVVQLGPWSSRIKKKTDAVAVPAAAGRWRARARAQDTSESAAVAKGSSLTPIVRTDAESRRTRWPTDDDDAEPLVDEIRAMLTSMSDGDISVSAYDTAWVGLVPRLDGGEGPQFPAAVRWIRNNQLPDGSWGDAALFSAYDRLINTLACVVTLTRWSLEPEMRGRGLSFLGRNMWKLATEDEESMPIGFELAFPSLIELAKSLGVHDFPYDHQALQAIYSSREIKVKRIPKEVMHTVPTSILHSLEGMPGLDWARLLKLQSSDGSFLFSPAATAYALMNTGDDRCFSYIDRTVKKFNGGVPNVYPVDLFEHIWAVDRLERLGISRYFQKEIEQCMDYVNRHWTEDGICWARNSDVKEVDDTAMAFRLLRLHGYSVSPDVFKNFEKDGEFFAFVGQSNQAVTGMYNLNRASQISFPGEDVLHRAGPFSYEFLRRKQAEGALRDKWIISKDLPGEVVYTLDFPWYGNLPRVEARDYLEQYGGGDDVWIGKTLYRMPLVNNDVYLELARMDFNHCQALHQLEWQGLKKWYTENRLMDFGVAQEDALRAYFLAAASVYEPCRAAERLAWARAAILANAVSTHLRNSPSFRERLEHSLRCRPSEETDGSWFNSSSGSDAVLVKAVLRLTDSLAREAQPIHGGDPEDIHKLLRSAWAEWVREKADAADSVCNGSSAVEQEGSRMVHDKQTCLLLARMIEISAGRAAGEAASEDGDRRIIQLTGSICDSLKQKMLVSQDPEKNEEMMSHVDDELKLRIREFVQYLLRLGEKKTGSSETRQTFLSIVKSCYYAAHCPPHVVDRHISRVIFEPVSAAK

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict34in Ref. 1; AAT70083/AAT70084
Sequence conflict45in Ref. 1; AAT70083/AAT70084
Sequence conflict47in Ref. 1; AAT70083/AAT70084
Sequence conflict52in Ref. 1; AAT70083/AAT70084
Sequence conflict233in Ref. 1; AAT70083/AAT70084
Sequence conflict242in Ref. 1; AAT70083/AAT70084
Sequence conflict271in Ref. 1; AAT70083/AAT70084
Sequence conflict441in Ref. 1; AAT70083/AAT70084
Sequence conflict451in Ref. 1; AAT70083/AAT70084
Sequence conflict541in Ref. 1; AAT70083/AAT70084
Sequence conflict657in Ref. 1; AAT70083/AAT70084

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY562490
EMBL· GenBank· DDBJ
AAT70083.1
EMBL· GenBank· DDBJ
Genomic DNA
AY562491
EMBL· GenBank· DDBJ
AAT70084.1
EMBL· GenBank· DDBJ
mRNA
CM007647
EMBL· GenBank· DDBJ
ONL99283.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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