A0A1D5R9L3 · A0A1D5R9L3_MACMU

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

L-ascorbate (UniProtKB | Rhea| CHEBI:38290 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentMLL3/4 complex
Molecular Functionchromatin DNA binding
Molecular Functionhistone H3K27me2/H3K27me3 demethylase activity
Molecular Functionmetal ion binding
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Biological Processregulation of gene expression

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    [histone H3]-trimethyl-L-lysine(27) demethylase
  • EC number

Gene names

    • Name
      UTY

Organism names

  • Taxonomic identifier
  • Strain
    • 17573
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca

Accessions

  • Primary accession
    A0A1D5R9L3

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

3D structure databases

Family & Domains

Features

Showing features for repeat, region, compositional bias, domain.

TypeIDPosition(s)Description
Repeat90-123TPR
Repeat127-160TPR
Repeat315-348TPR
Region473-496Disordered
Region662-731Disordered
Region764-790Disordered
Region855-909Disordered
Region1087-1123Disordered
Compositional bias1090-1120Basic and acidic residues
Domain1139-1302JmjC

Sequence similarities

Belongs to the UTX family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,446
  • Mass (Da)
    160,607
  • Last updated
    2019-12-11 v2
  • Checksum
    6C785F54264B9AB1
MNSCGVSLSAAAVALGDEAKKMAAGKASRDSEEESLSLTVEEREALGGMDSRLFGFVRLHEDGARMKTLLGKAVRCYESLILKAEGKVDSDFFCQLGHFNLLLEDYSKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSSAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDIVGDKASKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQAYRAHDPNTEPVLNHSQTPILQQSLSLHMITSSQVEGLSSPAKKKRTSSPTKNGSDNWNVVQSLSHHPVQQVYSLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKGVAQVRTTGIHNGAIADSSLPTNSVSDRQPHAALTRVSSISQPGVHPACIEKLLSNGAFSAGCVPCGTSKILGSTDTVLLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSIEEPWRKQRSNSAQGLHKSQSSCVSGPNEEQPLFSTESAQYQQATSTGIKKPNEHLTLPSNSVPQKNADSHFSSHIATSGGQQGIIFTKESKPSKHQSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLVGKANDNVGTGTCDKVNNIYPAVHTKTDHSVASSPSSAISTATPSPKSTEQASINSVTSLNSPHSGIHTINGEGLENSQSSTKVDLPLVSHRSTSQIIPSMSVSICPSSTEVLKAFRNLGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQCQTLREALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCQDCARKTSRSLENFVVLEQYKMEDLIQVYDQFTLVSDQHVSTLS

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
F7EHL6F7EHL6_MACMUUTY1444
A0A1D5Q8A7A0A1D5Q8A7_MACMUUTY1290
A0A1D5Q9J9A0A1D5Q9J9_MACMUUTY1412
A0A1D5Q7S4A0A1D5Q7S4_MACMUUTY1394
A0A1D5RCG7A0A1D5RCG7_MACMUUTY1347
F7EHK5F7EHK5_MACMUUTY1411
A0A1D5QCV5A0A1D5QCV5_MACMUUTY1399

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1090-1120Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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