A0A1D5PB14 · A0A1D5PB14_CHICK

  • Protein
    Mothers against decapentaplegic homolog
  • Gene
    SMAD6
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular ComponentGolgi apparatus
Cellular Componentheteromeric SMAD protein complex
Cellular Componentnuclear body
Molecular Functionchromatin binding
Molecular Functionco-SMAD binding
Molecular FunctionI-SMAD binding
Molecular Functionidentical protein binding
Molecular Functionmetal ion binding
Molecular Functionprotein sequestering activity
Molecular FunctionR-SMAD binding
Molecular Functiontranscription cis-regulatory region binding
Molecular Functiontranscription regulator inhibitor activity
Molecular Functiontype I activin receptor binding
Molecular Functiontype I transforming growth factor beta receptor binding
Molecular Functionubiquitin protein ligase binding
Biological Processanatomical structure morphogenesis
Biological Processaorta development
Biological Processaortic valve morphogenesis
Biological ProcessBMP signaling pathway
Biological Processcell differentiation
Biological Processcell-substrate adhesion
Biological Processcoronary vasculature development
Biological Processfat cell differentiation
Biological Processimmune response
Biological Processmitral valve morphogenesis
Biological Processnegative regulation of activin receptor signaling pathway
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of BMP signaling pathway
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of ossification
Biological Processnegative regulation of osteoblast differentiation
Biological Processnegative regulation of SMAD protein signal transduction
Biological Processnegative regulation of transforming growth factor beta receptor signaling pathway
Biological Processoutflow tract septum morphogenesis
Biological Processpositive regulation of miRNA transcription
Biological Processpulmonary valve morphogenesis
Biological Processregulation of transcription by RNA polymerase II
Biological Processresponse to laminar fluid shear stress
Biological Processresponse to lipopolysaccharide
Biological ProcessSMAD protein signal transduction
Biological Processtransforming growth factor beta receptor signaling pathway
Biological Processureteric bud development
Biological Processventricular septum development
Biological Processzygotic specification of dorsal/ventral axis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mothers against decapentaplegic homolog
  • Short names
    MAD homolog
    ; Mothers against DPP homolog
  • Alternative names
    • SMAD family member

Gene names

    • Name
      SMAD6

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Broiler
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    A0A1D5PB14

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Family & Domains

Sequence similarities

Belongs to the dwarfin/SMAD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    431
  • Mass (Da)
    47,657
  • Last updated
    2019-04-10 v2
  • Checksum
    5770CF1C52AF6EDB
MFRSKRSGLVRRLWRSRVIPERDGGDGNGQSSERNATAVTAEGQRMAQPRRAQEGEGRPVRCCLFAERPGPELPPPPPPPPPGGASPPGPGGGEARSRLVLLERELKAVTYALLKRLKERSLHSLLQAVESRGGTPGGCVLVARGELRLGGGQAAPPHLLLGKLFRWPDLQHPAELKALCECQSFGAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPNDEQKPLDLSDSTLSYTETEATNSPNVTPGEFSDASTSPDAVKRSHWCNVAYWEHRTRVGRLYTVYEQSVSIFYDLPQGNGFCLGQLNLENRSETVRRTRSKIGYGILLSKEPDGVWAYNRSEHPIFVNSPTLDIPNCRTLIVRKVMPGYSIKVFDYEKSCLLQHTAELDYADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLSNNR

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8V0YY43A0A8V0YY43_CHICKSMAD6412

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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