A0A1C7MLA2 · A0A1C7MLA2_GRIFR
- ProteinCTP synthase
- GeneURA7
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids641 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
Catalytic activity
- UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H+
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 419 | Nucleophile | |||
Active site | 570 | ||||
Active site | 572 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoophidium | |
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | CTP synthase activity | |
Molecular Function | identical protein binding | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | glutamine metabolic process | |
Biological Process | pyrimidine nucleobase biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCTP synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Grifolaceae > Grifola
Accessions
- Primary accessionA0A1C7MLA2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 3-138 | CTP synthase N-terminal | |||
Domain | 158-285 | CTP synthase N-terminal | |||
Domain | 330-588 | Glutamine amidotransferase | |||
Region | 622-641 | Disordered | |||
Sequence similarities
Belongs to the CTP synthase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length641
- Mass (Da)71,792
- Last updated2016-11-30 v1
- MD5 Checksum6EFA3BDA9476F6E2CAE2AE2D36C32EE9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LUGG01000002 EMBL· GenBank· DDBJ | OBZ77447.1 EMBL· GenBank· DDBJ | Genomic DNA |