A0A1C6DXV2 · A0A1C6DXV2_9CLOT

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site471Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA1
    • Synonyms
      hppA
    • ORF names
      SAMEA3545266_02684
      , SAMEA3545417_00926

Organism names

  • Taxonomic identifier
  • Strains
    • 2789STDY5608858
    • 2789STDY5834954
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Clostridiaceae > Clostridium > environmental samples

Accessions

  • Primary accession
    A0A1C6DXV2

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane57-74Helical
Transmembrane80-100Helical
Transmembrane121-144Helical
Transmembrane164-185Helical
Transmembrane265-285Helical
Transmembrane305-324Helical
Transmembrane330-350Helical
Transmembrane386-406Helical
Transmembrane413-432Helical
Transmembrane519-545Helical
Transmembrane586-604Helical
Transmembrane610-629Helical
Transmembrane677-698Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    699
  • Mass (Da)
    72,617
  • Last updated
    2016-11-02 v1
  • MD5 Checksum
    925A0DD7E6361EF40B83EFAAE370F2CD
MKLIVFAPVGATLALLFAAYYTYTIFKVDEGTDRMKYIASSIRKGANAFLKRQYKGVAIFFVIMFIILFILSRFNFVSIFMPFAFLTGGIFSGLSGYLGMKIATSANSRTANACTKSLNSGLRVAFSSGSVMGLVVVGLALADFSIWFGILNCYYSAMPLNERITMITTTMLTFSMGASSMALFARVGGGIFTKAADVGADLVGKVEIGIPEDDPRNPAVIADNVGDNVGDVAGMGADLYESYVGSILSSCALAVAAGLSVNGAVIPIVIASIGVMASILGSFFVKSKEDVSQKALLSALRRGTYFSAIVIAIASYFVVSNVLGKGHIGIYISILCGLVAGLLIGFFTEYYTSDNYNPTKSIAKSSETGAATVIITGLSVGMKSTAAPVIIIACSILISFVSSGGFNNFNMGLFGIAISAVGMLSTLGITLATDAYGPVADNAGGIAEMAGLPSEVRDRTDALDSLGNTTAATGKGFAIGSAALTALAFIASYKNSIEVLATNNNIAFEFDLSVLNPQVLIGAFIGAMVTFAFSSCTMSAVGRAASKIVVEVRRQFKEIKGLMDGKAEPDYASCVDICTKSSQKELIVIAVIAIATPLIVGFILGPNGVAGLLAGATICGFVLAVMMSNSGGAWDNAKKHIEAGNYGGKGSECHKGAVVGDTVGDPFKDTSGPALNILIKLMSIVSIVFGMVVLSFHIF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FMGV01000004
EMBL· GenBank· DDBJ
SCJ13452.1
EMBL· GenBank· DDBJ
Genomic DNA
FMHE01000026
EMBL· GenBank· DDBJ
SCJ94395.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help