A0A1C5MCU3 · A0A1C5MCU3_9CLOT
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids659 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 440 | Determinant of potassium dependence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Clostridiaceae > Clostridium > environmental samples
Accessions
- Primary accessionA0A1C5MCU3
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 57-87 | Helical | |||
Transmembrane | 121-147 | Helical | |||
Transmembrane | 230-263 | Helical | |||
Transmembrane | 284-302 | Helical | |||
Transmembrane | 308-329 | Helical | |||
Transmembrane | 350-375 | Helical | |||
Transmembrane | 381-402 | Helical | |||
Transmembrane | 446-466 | Helical | |||
Transmembrane | 478-497 | Helical | |||
Transmembrane | 545-565 | Helical | |||
Transmembrane | 571-589 | Helical | |||
Transmembrane | 636-658 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length659
- Mass (Da)67,358
- Last updated2016-11-02 v1
- MD5 Checksum1B0DF0C1E8E1A01FF76BD4C55B7BF470
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FMEG01000002 EMBL· GenBank· DDBJ | SCH10260.1 EMBL· GenBank· DDBJ | Genomic DNA |