A0A1C5MCU3 · A0A1C5MCU3_9CLOT

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site440Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA1
    • Synonyms
      hppA
    • ORF names
      SAMEA3545337_00552

Organism names

  • Taxonomic identifier
  • Strain
    • 2789STDY5834871
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Clostridiaceae > Clostridium > environmental samples

Accessions

  • Primary accession
    A0A1C5MCU3

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane57-87Helical
Transmembrane121-147Helical
Transmembrane230-263Helical
Transmembrane284-302Helical
Transmembrane308-329Helical
Transmembrane350-375Helical
Transmembrane381-402Helical
Transmembrane446-466Helical
Transmembrane478-497Helical
Transmembrane545-565Helical
Transmembrane571-589Helical
Transmembrane636-658Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    659
  • Mass (Da)
    67,358
  • Last updated
    2016-11-02 v1
  • MD5 Checksum
    1B0DF0C1E8E1A01FF76BD4C55B7BF470
MENMMFLVPVAAVLALLFAAYLAAKVSKEDVGTDRMKEIADAIAEGARAFLMAEYKILVIFVAVLFVLIGFGISWVTAVCFVVGALFSTIAGYCGMTVATKANVRTANAARTSGMNKALSIAFSGGAVMGMCVAGLGALGVSIVYIVTKNVDVLSGFSLGASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSLVSALTLGAVTATVSGVLFPLAIAACGLIASILGTFFVKGGENANPQKALTKGDYASAIIVVIASVVLSKVLFDGFEAAIAVIAGLIVGVIIGNVTEYYTSADYNPVKKIGEQSETGAATTIISGLAVGMQSTAIPLLLICVAIFISYKVDGLYGIALAAVGMLSTTGITVAVDAYGPIADNAGGIAEMSGLDDSVREITDKLDSVGNTTAAMGKGFAIGSAALTALALFVSYAQAVQLDSIDLLSYKVIIGIFIGGMLTFLFSAFTMESVSKAAYKMIEEVRRQFREKPGIMKGEDKPDYTSCVSISTSAALHEMLLPGLMAVIVPLLVGIVLGVESLGGLLAGALVTGVLMAIFMSNAGGAWDNAKKYIEEGNHGGKGSEAHKAAVVGDTVGDPFKDTSGPSINILIKLMTVVSLVFAPLFLSIGGLL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FMEG01000002
EMBL· GenBank· DDBJ
SCH10260.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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