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A0A1C3D2N5 · A0A1C3D2N5_GEOTH

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11NADPH (UniProtKB | ChEBI)
Binding site12NADPH (UniProtKB | ChEBI)
Binding site32NADPH (UniProtKB | ChEBI)
Binding site33NADPH (UniProtKB | ChEBI)
Binding site49NADPH (UniProtKB | ChEBI)
Binding site106NADPH (UniProtKB | ChEBI)
Binding site106sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site136sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site138sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site140NADPH (UniProtKB | ChEBI)
Active site192Proton acceptor
Binding site192sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site245sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site255sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site256NADPH (UniProtKB | ChEBI)
Binding site256sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site257sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site280NADPH (UniProtKB | ChEBI)
Binding site282NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglycerol-3-phosphate dehydrogenase (NADP+) activity
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA
    • ORF names
      C1N76_14685

Organism names

Accessions

  • Primary accession
    A0A1C3D2N5

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    344
  • Mass (Da)
    36,831
  • Last updated
    2017-01-18 v1
  • MD5 Checksum
    8B0EFDCF4074B2E6935938EBF8DE9404
MENIAVLGAGSWGTALALVLADNGHHVRLWGHRTEQISEINEKRTNEKYLPGVRLPDAIIGYDDLCAALDGVAIVVLAVPTKAIRSVLADVRACLAKPITIVAVSKGIEPGTHKRVSEMVAEEMGEWLADVVVLSGPSHAEEVVLRHPTTVAVSSPNMEAARRIQDIFMNHHYFRVYTNPDLIGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGLTGVGDLIVTCTSVHSRNWRAGYMLGQGKKLDEVLESMGMVVEGVRTTKAAYELAKELGVKMPITEALYDVLFAGKDPKEAVDSLMARGKKEEMDDLNNIFAEQE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP027303
EMBL· GenBank· DDBJ
AWO75631.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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