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A0A1B9H3J2 · A0A1B9H3J2_9TREE

Function

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site430Nucleophile
Active site516
Active site518

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functiondihydroorotase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process
Biological Processcitrulline biosynthetic process
Biological Processglutamine metabolic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Carbamoyl-phosphate synthase, large subunit

Gene names

    • ORF names
      I316_00052

Organism names

  • Taxonomic identifier
  • Strain
    • BCC8398
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Kwoniella

Accessions

  • Primary accession
    A0A1B9H3J2

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-25Disordered
Domain692-884ATP-grasp
Domain1227-1418ATP-grasp
Domain1483-1635MGS-like

Sequence similarities

In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,346
  • Mass (Da)
    255,997
  • Last updated
    2016-11-02 v1
  • MD5 Checksum
    54B8180CA22FE38735D801CACB63B9DD
MVPPPVPGFEGVVPSSDIPPIQQASSIAPAIHAAVEVTPPSSPAPAASSPRPVVQRASSYVAPAPKPLGSLYPPATLKGIDYEGMPDEPKWEDEMGEPDMVLELADGLALSGHSFGAKKSVAGECVFQTGMVGYPESLTDPSYSSQILILTYPLVGNYGVPERPNTETSKIPTSQDAHNVPPPTHLLDSLPLEFESSHIHISALVVANYHPSFSHHLANSSLGTWLKEQGIPAIWGVDTRMLTKKLREGGVLLGRVLAKQGSNAVDGERGRETQTGVLGGVSRLLNGLSAPSMVRSNSTDNFALNWREDYETVPFHDPNGINLVAKVSTEQPTLYTAVTGSDKKVHPRTGKQLRVIAIDVGMKWNQIRCFRERGVEVKVVPWNYDINAETEHYDGLFVSNGPGDPSMVKETISNLSRALENSKVPVFGICLGHQLLALASGASTRKMKYGNRGMNLPCTCSTSGRCYITSQNHGYEVDVSTLKNGWEPLFTNANDNSNEGIWMGKNGKPFFSVQFHPESAPGPRDTEFLFDVFIQSMVDCAREGKLVPIDMPGGELAANIALRPKEQVKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILVNPNIATIQTSKGLADKVYFLPVTPDFVRKIIKHEKPDGIYCTFGGQTALSVGIKLKDEFAGLGVKVLGTPIETVITTEDRDLFAKAMEEIGEKCAESASAVNLEEAKEAANRIGYPVIIRAAFALGGLGSGFAQNDEELTELCNKAFATSPQVLVEKSMKGWKEIEYEVVRDCRNNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDADYNMLRTTAVNVIRHLGVIGECNIQYALNPFSKEYCIIEVNARLSRSSALASKATGYPLAFIAAKLGLNIPLNEIKNSVTKLTSACFEPSLDYCVVKIPRWDLKKFNRVSTALSSSMKSVGEVMAIGRTFEETIQKAIRCIDDQFPGFGEHTVVDDIDYEIANPTDKRLFAIATAFKRGYSVDKINQMSNIDKWFLTRLERLSKTEKVISNYNASTVPNQLIRNAKQLGFSDRQIAKALNSNELAVRRLRIEAGISPFVKQIDTVAAEFPAFTNYLYTTYNASEHDVTFDDNGVMVLGSGVYRIGSSVEFDWCAVRAIRTIREQGLKTVMINYNPETVSTDYDEADKLYFENISLETVLDIYDIERSSGIVLSMGGQTPNNIALNLHRQNVKIYGTSPEMIDTAENRYKFSRMLDKIGVDQPLWKELTSFSEAKSFCDKVSYPVLVRPSYVLSGAAMNVVFSEDDLESYLSQATDVSRDHPVVISKYIEEAKEIEMDAVAKDGKMVMHYISEHVENAGVHSGDATLILPPQDLDPETIRKIEIATQKIGQALNVTGPYNIQFIAKNNEIKVIECNLRAARSFPFVSKVTNIDAIELATKVMLGFPVTPYPDVKMPPNYVGVKVPQFSFSRLSGADPVLGVEMASTGEVACFGKDKYDAYLKALISTGIRPPKKNILLSVGSFKEKLEMLPAVHKLHRQGYNLFATAGTSDFFQEHGIPVKFLEALGSDNDLNPQKAEYSLTQHLANNLIDLYINLPSKNRSRRPASYISQGYKSRRMAVDFAVPLITNVKCAKLFIEAVLKKPTLDITSVDYKTSHQTFTFPSLVSVQAFVPGAAESGSNDFGEASQAAIRGGFTVMQMVPQGVNSAVEDEISLQRAQSNASGAAHCDYFFSVAATADNASRLQDAVLAGAKALFIPFNNFFGTVNKVTSVAQHFAAWPADKPIVTDARSTDLASILLLASLNNRSIHIASVSTRDDILLIALAKEKGLNVTCDVSIYALFYSQADYPTAQCLPTADDQHALWDHLSTIDIFSVGVLPYELGTALGKPVSASSGVAESLPLLLTAVAEGKLTLEDISLRLSENPRNIFGLPEQAQTYVEVEVNRRSHFSSEQPEATWSPLEGKSIAGAIHRVVINSHSVLLDGTSFSMPLGRDISATGPRASKQSRGSFAMQKRPSIAALVSPTQERPASFGPPATDKLMSLSVHAPVNTSPVRSLLSLQTSPAFARRHILSVKQFDREDLHVLFNLASEMRAQVERTGSVDTLRGRVLCTLFYEPSTRTSTSFEAAMKRCGGEVVQVTASTSSVQKGESLADTIRTVGCYSDAIVLRHPAVGSSKSAAKSSPVPIINAGDGIGEHPTQSLLDVFCIREELGSVNGITVTLIGDLKNGRTVHSLVKLLSLYDVTINFVSPPSLTMPDSVKTEASRAGVRWTESHSLSEEIIAKSDVLYATRVQKERFDNIAEYEAVKDIYVINNDVLAKAKESAIVMHPLPRLNEIDPEVDFDSRRAAYFRQMRYGLFVRMALLTLVLGA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KI669492
EMBL· GenBank· DDBJ
OCF37828.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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