A0A1B8J8S0 · A0A1B8J8S0_9HELI
- ProteinDNA-directed DNA polymerase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids875 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | DNA polymerase III complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | metal ion binding | |
Biological Process | DNA replication |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed DNA polymerase
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Helicobacteraceae > Helicobacter
Accessions
- Primary accessionA0A1B8J8S0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 36-178 | AAA+ ATPase | ||||
Sequence: IVHAYLFSGLRGSGKTSSARIFARALVCEKGPISTPCGECDICKATLEGRNLDIIEKDAASNRGIDDIKDIIEHTRYAPSMSRYKIFIIDEVHMLTKEAFNALLKTLEEPPEYVKFILATTDPLKLPATIISRTQHFRFKKIP | ||||||
Region | 388-429 | Disordered | ||||
Sequence: ESKIADSSGVDSSANVDSGVPNTSTQTQATQTTTTQAPTTQT | ||||||
Compositional bias | 393-429 | Polar residues | ||||
Sequence: DSSGVDSSANVDSGVPNTSTQTQATQTTTTQAPTTQT | ||||||
Region | 523-606 | Disordered | ||||
Sequence: DALNPQNPASAPNVANAPTQAQTSQDDLPQKKTSDLSLEPSTSANPTPNTQAPQAQQTAPRADFVDSSTFSDSSTSANFGAPNA | ||||||
Compositional bias | 639-676 | Polar residues | ||||
Sequence: SAQAGNAESTSQDFANSANLANPANSTNSSNLANPAQE | ||||||
Region | 639-678 | Disordered | ||||
Sequence: SAQAGNAESTSQDFANSANLANPANSTNSSNLANPAQEPM | ||||||
Compositional bias | 695-741 | Polar residues | ||||
Sequence: IPTAPTPPAQENITPSFTQEYPPTTPATLSAPNTQNMGAQNQDSAPD | ||||||
Region | 695-749 | Disordered | ||||
Sequence: IPTAPTPPAQENITPSFTQEYPPTTPATLSAPNTQNMGAQNQDSAPDTPKIDVPK | ||||||
Region | 770-837 | Disordered | ||||
Sequence: PNSSQNFSQNPNANPSPDFSQNANLDYQNHVPESSKNLDSSAYAPASDNQNAAPAPSQTQPQNAAQSQ |
Sequence similarities
Belongs to the DnaX/STICHEL family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length875
- Mass (Da)94,716
- Last updated2016-11-02 v1
- Checksum2ED029DDA6D41284
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 393-429 | Polar residues | ||||
Sequence: DSSGVDSSANVDSGVPNTSTQTQATQTTTTQAPTTQT | ||||||
Compositional bias | 639-676 | Polar residues | ||||
Sequence: SAQAGNAESTSQDFANSANLANPANSTNSSNLANPAQE | ||||||
Compositional bias | 695-741 | Polar residues | ||||
Sequence: IPTAPTPPAQENITPSFTQEYPPTTPATLSAPNTQNMGAQNQDSAPD |
Keywords
- Technical term