A0A1B8J7N5 · A0A1B8J7N5_9HELI

  • Protein
    Phosphopantetheine adenylyltransferase
  • Gene
    coaD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site11substrate
Binding site11-12ATP (UniProtKB | ChEBI)
Binding site19ATP (UniProtKB | ChEBI)
Site19Transition state stabilizer
Binding site43substrate
Binding site75substrate
Binding site89substrate
Binding site90-92ATP (UniProtKB | ChEBI)
Binding site100ATP (UniProtKB | ChEBI)
Binding site125-131ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • ORF names
      BA723_01185
      , BKN38_01875

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • HMC1
    • CLO-3
  • Taxonomic lineage
    Bacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Helicobacteraceae > Helicobacter

Accessions

  • Primary accession
    A0A1B8J7N5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-135Cytidyltransferase-like

Sequence similarities

Belongs to the bacterial CoaD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    162
  • Mass (Da)
    18,262
  • Last updated
    2016-11-02 v1
  • Checksum
    08D4D132FB944943
MKHKIGIYPGTFDPLTNGHLDIIKRSCEIFDNVILAIAHSASKQPLFSIEERLEMARLVTSDFDNVCCIEFGGLLADLAKEYNAKILIRGLRVVSDFEYELQMGYTNTSLNPELDTIYFMPTLQNAFISSSIVRNILSHRGKISHLIPSAAFAYIKDKMPCM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MAMQ01000083
EMBL· GenBank· DDBJ
OBV28968.1
EMBL· GenBank· DDBJ
Genomic DNA
MLQN01000004
EMBL· GenBank· DDBJ
OHU84813.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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