A0A1B8DFJ4 · A0A1B8DFJ4_9PEZI

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Confers resistance to H2O2 in hyphae. May play an antioxidative role in fungal defense against the host-produced H2O2 (oxidative burst) at the early stage of plant infection.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site144Transition state stabilizer
Active site148Proton acceptor
Binding site323Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentextracellular region
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      VE04_02490

Organism names

  • Taxonomic identifier
  • Strain
    • 24MN13
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Thelebolales > Thelebolaceae > Pseudogymnoascus

Accessions

  • Primary accession
    A0A1B8DFJ4

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, cross-link.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_500844794824-794Catalase-peroxidase
Cross-link282↔308Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-147)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Keywords

Interaction

Subunit

Homodimer; disulfide-linked.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region47-74Disordered
Domain142-467Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    794
  • Mass (Da)
    86,988
  • Last updated
    2016-11-02 v1
  • Checksum
    E9DB7B71A6F17FFA
MLQLMPLGQIVLLAISALPLTSAVSCPYIGGNGARDNAPRIPHPESIVEPRYSPEGPGFGRCPKKSKVAGGGTRSEDWWPCDLSLAVLRQNGESSNPWDAKFNYATEFAKLDVSELKKDLTELQTNSQSWWPADFGNYGPFLVRLSWHNAGTYRSEDGRGGAGMGQQRFAPLNSWPDNAGLDKARRLLWPIKQKYGRKLSWADLMVFAGNTAMENMGFPTYGFAFGREDTWQSDEGIFWGSEQEFFPSPNSNKDRYNGSADIHGRAKNLEEPLSAANMGLIYVDPRGPNGTPDPKASALDIRVTFGRMGMDDEETVALIAGGHAFGKTHGAVSGDFIGPEPNAAGIENQGLGWKNSFNTGVGNNSYTSGLEVIWSKTPTKWANEFLGSLIHNNWTLVKSPDGAPQWEAVNANASYPDAFITGKLHKPTMLTSDLALIHDPIYNNVSKKFLNDFDYFTEKFALAWYKLLHRDMGPVTRYLGSEVPKDEHLLWQDPLPAASYKTIDDADVKRLKKDILSAPNVNISNLITTAWGSASTFRISDKRGGANGARIALKPQRSFAVNNPDRVAVVLKSLQAVKDKFNSANKKKQVSLADLIVLGGTAAVEKAAADAGTAIKVPFTPGRVDTTQDLTDVETFAYLEPRSDAFRNYGHGNSRSLTEEMMVSRAALLTLSIPEMTVLVGGMRALDANYDGSAFGILTDRPGQLTNDFFTNLLDASTVWSPVADTNGEKFEGKDLSTESPKYKATRADLIFGSHAELRAVAEVYGSGDAQDKFVNDFARAWVKVMDLDRYDVR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV456018
EMBL· GenBank· DDBJ
OBT57928.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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