A0A1B7YPJ0 · A0A1B7YPJ0_COLHI

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site153substrate
Binding site175ATP (UniProtKB | ChEBI)
Binding site175Mg2+ (UniProtKB | ChEBI)
Binding site177Mg2+ (UniProtKB | ChEBI)
Binding site179-182substrate
Binding site255-257substrate
Binding site261substrate
Binding site320-323substrate
Binding site359ATP (UniProtKB | ChEBI)
Binding site426-435ATP (UniProtKB | ChEBI)
Binding site430Mg2+ (UniProtKB | ChEBI)
Binding site437ATP (UniProtKB | ChEBI)
Binding site459-462ATP (UniProtKB | ChEBI)
Binding site485ATP (UniProtKB | ChEBI)
Binding site512substrate
Binding site514ATP (UniProtKB | ChEBI)
Binding site520ATP (UniProtKB | ChEBI)
Binding site523-524substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglutathione binding
Molecular Functionglutathione synthase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione synthetase
  • EC number
  • Short names
    GSH-S

Gene names

    • ORF names
      CH63R_02665

Organism names

Accessions

  • Primary accession
    A0A1B7YPJ0

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain246-356Glutathione synthase substrate-binding

Sequence similarities

Belongs to the eukaryotic GSH synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    536
  • Mass (Da)
    59,185
  • Last updated
    2016-11-02 v1
  • Checksum
    01B3316E15822930
MATSTLTKEQYPPRLSQAEQDALVQTVKDWTIGNGLSVRPPANVVSPESDPKGILAVNVPVTLFPSPFPRSCFEQARSVQKTYNELYAAISRDEDFLSAMVNEVKGGDDFISKLWDTHVRVKKEGYTQVKNIDSISRHPKTNAVKQLSLGLFRSDYLVHQDTTSGEPKRQVKQVEFNTIASSFGGLSSRTSLLHKFLSVAEYPLLESPIESGSLELPENKSVQGLSGGIRAAFNAYGPSELGHKKCVIFVVQGGERNIFDQRHLEYALASSPDDPVPVFRIPCSELLQHTEVAATPKRQLLYKLPRDPSKVFEVAVAYLRCWYDPSDYPDESAWEARYHLEKSAAVKCPTVLTQLAGSKKIQQVLATPRSGSSPSVLGRFIPDDAPQTAEVFQTFTNIFPMDTSEAGLKARKIAQDPELCRNYVLKPQREGGGNNHYREDIPEFLKKTPETHWGSYILMELITPPKQDNVILRNGNLEEGGVICELGIYGTAVWDQSTGEVVHNEDAGYLLRTKGDTSNEGGVAAGFGCMDSCALV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LTAN01000002
EMBL· GenBank· DDBJ
OBR13939.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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