A0A1B7Y9C8 · A0A1B7Y9C8_COLHI
- ProteinGlutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids488 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Catalytic activity
- L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H+
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 44 | Charge relay system | ||||
Sequence: K | ||||||
Active site | 120 | Charge relay system | ||||
Sequence: S | ||||||
Active site | 144 | Acyl-ester intermediate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | glutamyl-tRNA(Gln) amidotransferase complex | |
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | |
Molecular Function | transferase activity | |
Biological Process | glutaminyl-tRNAGln biosynthesis via transamidation | |
Biological Process | mitochondrial translation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
- EC number
- Short namesGlu-AdT subunit A
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Glomerellales > Glomerellaceae > Colletotrichum > Colletotrichum destructivum species complex
Accessions
- Primary accessionA0A1B7Y9C8
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 41-476 | Amidase | ||||
Sequence: LAVKDNIATHGLPTTCSSAILSSHKSPYEATIVRQLRDRGAHVVGKTNMDEFGMGSHSLNSVHGPVLNPLSATPTSAGGSSGGSAVAVQTGEADVALGTDTGGSIRLPAAYCGVVGYKPSYGMLSRFGVVPYANSLDTVGLLAREVGVIEDLMFSTGLDGEHDAQDPTSLSESFRKRQQAQGGTDRRSRLRIGIPIEYNIEELDPQIRTAWSDAADLLQQSGIDVVPVSLPSTKHALSAYYVIAPAEASSNLAKFDGVRYGTRGDESDGAGEVLYSKTRGLGFGDEVRRRILLGSYSLSSEAMDNYFLQAQRVRRLVQRDFDRVFRRPNPLYDERQFDLSDMGDGVELQDKLGPSQVDFLLCPTAPTFAPRIDEVRRQTPVQVYMNDVFTVPASLAGLPAVSIPKKVESHDAEADESRKVAGLQLIGQYWDDRRLL | ||||||
Region | 198-227 | Disordered | ||||
Sequence: LDGEHDAQDPTSLSESFRKRQQAQGGTDRR |
Sequence similarities
Belongs to the amidase family. GatA subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length488
- Mass (Da)52,773
- Last updated2016-11-02 v1
- Checksum11D715B8FACB05FE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LTAN01000005 EMBL· GenBank· DDBJ | OBR08577.1 EMBL· GenBank· DDBJ | Genomic DNA |