A0A1B7Y1P1 · A0A1B7Y1P1_COLHI

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site108L-glutamate (UniProtKB | ChEBI)
Active site386Nucleophile
Binding site404-406L-glutamate (UniProtKB | ChEBI)
Binding site428L-glutamate (UniProtKB | ChEBI)
Binding site456-457L-glutamate (UniProtKB | ChEBI)
Binding site479L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      CH63R_10055

Organism names

Accessions

  • Primary accession
    A0A1B7Y1P1

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-27
ChainPRO_500860127028-575Glutathione hydrolase

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    575
  • Mass (Da)
    61,751
  • Last updated
    2016-11-02 v1
  • Checksum
    8DCA4BCA3A9AD7C9
MKPSSSHSTWRCYASLLLLAELRSTSAATVPQFVFNPHAGSSGAVASEAVECSKIGRDLIARGGNAVDALVGTTFCVGTVGMYHSGIGGGGFVVVRDAYGNYESVDFRESAPAAAFQDMYKGNIEGSVYGGLAVGVPSEVRGLEYIHKKYGVLPWKAVVTPAAQLATTGFRVSEDLVRYMANAINGQYNFLVEDPVWAEEFAPNGKLLQLGDTIYRKRYGAHTSTLAKIAEEGPDAFYSGPIAESIIATVRATNGSLTLDDLSSYKVVTRPSLSISYRGHRLVSVGSPASGAVCLNTLKIMEQFDPSESADTHLGVHRFDEALRFAYGARSLLGDPDFVDGIGPFEDTLIDEATAKDIRHRILDNQTQPVDRYDPHGMYASEGFGTSHIVTADKSGMATSLTTTVNLLFGAQIMDPLSGVILNNEMNDFSIPGVRNAFGFEPSPANFVRANKRPLSSITPVIVEHPDGTLYATVGAAGGSRIISSTAQVAWHVLEHGRTMKQALREPRLHDQLMPNTVTFEYAFDNDTVASMIEKGHDVTWVPEGRSAVQGIIFDGGVFEAASEPRQKNSGAFTV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LTAN01000007
EMBL· GenBank· DDBJ
OBR05935.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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