A0A1B7XY13 · A0A1B7XY13_COLHI
- Proteinpyruvate carboxylase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1339 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
Catalytic activity
- hydrogencarbonate + pyruvate + ATP = oxaloacetate + ADP + phosphate + H+
Cofactor
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pyruvate carboxylase activity | |
Biological Process | gluconeogenesis | |
Biological Process | pyruvate metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namepyruvate carboxylase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Glomerellales > Glomerellaceae > Colletotrichum > Colletotrichum destructivum species complex
Accessions
- Primary accessionA0A1B7XY13
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-30 | Disordered | ||||
Sequence: MYTPPSQSSPKPDRSQNQLLNQPRQPNSRR | ||||||
Domain | 128-638 | Biotin carboxylation | ||||
Sequence: HLKKILVANRGEIRKCLRSTEPLTHGRLTVIQPFVYVLSNLVPAQDLQNRKLSHCPSPSLPPRYCGPRPSADFLRPMSCHCTPSQSSVMRTVSPCTDRCSTEADEAYVIGKRGQYTPVGAYLAGDEIIKIAVEHGAQMVHPGYGFLSENAEFARNVEKAGLIFVGPSADVIDSLGDKVSARKLAIAANVPVVPGTEGAVATFEEVKGFTDQYGFPIIIKAAYGGGGRGMRVVREQESLKESFERATSEAKSAFGNGTVFVERFLDKPKHIEVQLLGDNHGNIVHLYERDCSVQRRHQKVVEIAPAKDLPSDVRDAILNDAVRLAKSVNYRNAGTAEFLVDQQNRYYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGATLQQLGLTQDRISTRGFAIQCRITTEDPSKGFQPDTGKIEVYRSAGGNGVRLDGGNGFAGAVITPFYDSMLVKCTCHGSTYEIARRKVLRALVEFRIRGVKTNIPFLASLLTHPTFIDGNCWTTFIDDTPQ | ||||||
Domain | 308-505 | ATP-grasp | ||||
Sequence: RKLAIAANVPVVPGTEGAVATFEEVKGFTDQYGFPIIIKAAYGGGGRGMRVVREQESLKESFERATSEAKSAFGNGTVFVERFLDKPKHIEVQLLGDNHGNIVHLYERDCSVQRRHQKVVEIAPAKDLPSDVRDAILNDAVRLAKSVNYRNAGTAEFLVDQQNRYYFIEINPRIQVEHTITEEITGIDIVAAQIQIAA | ||||||
Domain | 724-992 | Pyruvate carboxyltransferase | ||||
Sequence: TLLMDTTWRDAHQSLLATRVRTVDLLNIAKETSHGLSNLYSLECWGGATFDVAYRFLYEDPWDRLRRMRKAVPNIPFQMLLRGANGVAYSSLPDNAIDHFVEQAKKNGVDIFRVFDALNDIDQLEVGIKAVHKAGGVVEGTVCYSGDMLNPKKKYNLDYYLELVDKLVALDIHVLGIKDMAGVLKPHAATLLIGAIRKKYPDLPIHVHTHDSAGTGVASMVACAKAGADAVDAATDSLSGMTSQPSINAIIASLEGSDNDTGLNPAHVR | ||||||
Domain | 1262-1337 | Lipoyl-binding | ||||
Sequence: KADPSDSSQVGAPMAGVLVELRVKEGTDVKKGDPIAVLSAMKMEMVISAPHNGKVATLQVKEGDSVDGSDLVCRIV |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,339
- Mass (Da)146,645
- Last updated2016-11-02 v1
- Checksum7ACCED7688E99476
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LTAN01000008 EMBL· GenBank· DDBJ | OBR04656.1 EMBL· GenBank· DDBJ | Genomic DNA |