A0A1B7XY13 · A0A1B7XY13_COLHI

Function

function

Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

biotin (UniProtKB | Rhea| CHEBI:57586 )

Pathway

Carbohydrate biosynthesis; gluconeogenesis.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpyruvate carboxylase activity
Biological Processgluconeogenesis
Biological Processpyruvate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    pyruvate carboxylase
  • EC number

Gene names

    • ORF names
      CH63R_11359

Organism names

Accessions

  • Primary accession
    A0A1B7XY13

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-30Disordered
Domain128-638Biotin carboxylation
Domain308-505ATP-grasp
Domain724-992Pyruvate carboxyltransferase
Domain1262-1337Lipoyl-binding

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,339
  • Mass (Da)
    146,645
  • Last updated
    2016-11-02 v1
  • Checksum
    7ACCED7688E99476
MYTPPSQSSPKPDRSQNQLLNQPRQPNSRRNCLAAETSTAFYCSSSSSSSYSSARTNKYLLGTAEAPESLPVPAASLSSPSKPSHSQLPIMAQTAVTFNDVFEEGDVEEVQKDPQTIHHIRANSSIMHLKKILVANRGEIRKCLRSTEPLTHGRLTVIQPFVYVLSNLVPAQDLQNRKLSHCPSPSLPPRYCGPRPSADFLRPMSCHCTPSQSSVMRTVSPCTDRCSTEADEAYVIGKRGQYTPVGAYLAGDEIIKIAVEHGAQMVHPGYGFLSENAEFARNVEKAGLIFVGPSADVIDSLGDKVSARKLAIAANVPVVPGTEGAVATFEEVKGFTDQYGFPIIIKAAYGGGGRGMRVVREQESLKESFERATSEAKSAFGNGTVFVERFLDKPKHIEVQLLGDNHGNIVHLYERDCSVQRRHQKVVEIAPAKDLPSDVRDAILNDAVRLAKSVNYRNAGTAEFLVDQQNRYYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGATLQQLGLTQDRISTRGFAIQCRITTEDPSKGFQPDTGKIEVYRSAGGNGVRLDGGNGFAGAVITPFYDSMLVKCTCHGSTYEIARRKVLRALVEFRIRGVKTNIPFLASLLTHPTFIDGNCWTTFIDDTPQLFDLIGSQNRAQKLLAYLGDVAVNGSSIKGQIGEPKFKGDIILPELLNDDGSKVDVTQTCTKGWRQIILEQGPKAFAKAVRDYKGTLLMDTTWRDAHQSLLATRVRTVDLLNIAKETSHGLSNLYSLECWGGATFDVAYRFLYEDPWDRLRRMRKAVPNIPFQMLLRGANGVAYSSLPDNAIDHFVEQAKKNGVDIFRVFDALNDIDQLEVGIKAVHKAGGVVEGTVCYSGDMLNPKKKYNLDYYLELVDKLVALDIHVLGIKDMAGVLKPHAATLLIGAIRKKYPDLPIHVHTHDSAGTGVASMVACAKAGADAVDAATDSLSGMTSQPSINAIIASLEGSDNDTGLNPAHVRALDSYWSQLRLLYSPFEAHLSGPDPEVYEHEIPGGQLTNMMFQASQLGLGTQWAETKKAYEHANDLLGDIVKVTPTSKVVGDLAQFMVSNKLSAEDVKARASELDFPGSVLEFLEGLMGQPYGGFPEPLRSNALRGRRKLDKRPGLFLEPVDFVKVKRELHKKFGGPVTECDIAAYVMYPKVFEDYKKFIQKYGDLSVLPTKYFLSRPEIGEEFHVELEKGKVLILKLLAIGPLSENTGQREVFYEMNGEVRQVTVDDNKASVENVSRLKADPSDSSQVGAPMAGVLVELRVKEGTDVKKGDPIAVLSAMKMEMVISAPHNGKVATLQVKEGDSVDGSDLVCRIVKA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LTAN01000008
EMBL· GenBank· DDBJ
OBR04656.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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