A0A1B1QC34 · A0A1B1QC34_9ASPA

  • Protein
    ATP-dependent Clp protease proteolytic subunit
  • Gene
    clpP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.

Catalytic activity

  • Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
    EC:3.4.21.92 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

120520406080100120140160180200
TypeIDPosition(s)Description
Active site101
Active site101Nucleophile
Active site126

GO annotations

AspectTerm
Cellular Componentendopeptidase Clp complex
Cellular Componentplastid
Molecular FunctionATP-dependent peptidase activity
Molecular FunctionATPase binding
Molecular Functionserine-type endopeptidase activity
Biological Processprotein quality control for misfolded or incompletely synthesized proteins

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent Clp protease proteolytic subunit
  • EC number
  • Alternative names
    • Endopeptidase Clp

Gene names

    • Name
      clpP

Encoded on

  • Plastid

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Asparagales > Orchidaceae > Epidendroideae > Neottieae > Neottia

Accessions

  • Primary accession
    A0A1B1QC34

Subcellular Location

Keywords

Interaction

Subunit

Component of the chloroplastic Clp protease core complex.

Family & Domains

Sequence similarities

Belongs to the peptidase S14 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    205
  • Mass (Da)
    22,998
  • Last updated
    2016-11-02 v1
  • Checksum
    403F5BF322F1078F
MPIGVPKVPFRSPGEEDAAWVDVYNRLYRERLLFLGQEVESEISNQLVGLMVYLSIEDNTRDLYLFINSPGGWVIPGIAIYDTMQFVPPDVHTICMGLAASMGSFILVGGEITKRLAFPHARVMIHQPASSFYESQAGEFMLEAEELLKLRETLTKVYVQRTGNPLWVISEDMERDIFMSATEAQAYGIVDLVAIENENIGGDFV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KU551268
EMBL· GenBank· DDBJ
ANT72828.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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