A0A1B1M0P9 · A0A1B1M0P9_PLADU
- ProteinAdenomatous polyposis coli
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2946 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | beta-catenin destruction complex | |
Cellular Component | catenin complex | |
Cellular Component | cytoplasmic microtubule | |
Cellular Component | intracellular membrane-bounded organelle | |
Molecular Function | beta-catenin binding | |
Molecular Function | gamma-catenin binding | |
Molecular Function | microtubule binding | |
Biological Process | cell fate specification | |
Biological Process | cell migration | |
Biological Process | negative regulation of canonical Wnt signaling pathway | |
Biological Process | negative regulation of microtubule depolymerization | |
Biological Process | nervous system development | |
Biological Process | pattern specification process | |
Biological Process | positive regulation of protein catabolic process | |
Biological Process | regulation of cell differentiation | |
Biological Process | Wnt signaling pathway |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Annelida > Polychaeta > Errantia > Phyllodocida > Nereididae > Platynereis
Accessions
- Primary accessionA0A1B1M0P9
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, compositional bias, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 239-272 | Disordered | ||||
Sequence: DQLRDSPDEDEDAENQDSNKKATGHGSADIDHHP | ||||||
Compositional bias | 252-266 | Basic and acidic residues | ||||
Sequence: ENQDSNKKATGHGSA | ||||||
Repeat | 350-378 | ARM | ||||
Sequence: TCMKALVAQLQSSNEDLRQVAASVLRNLS | ||||||
Repeat | 486-514 | ARM | ||||
Sequence: GCLQILLKHLRSPSLTIVSNACGTLWNLS | ||||||
Region | 666-726 | Disordered | ||||
Sequence: SPSRPVSRSGSQDSVGSVHSDISHDRVRTHNVLAKSNRLLTERQNMNSDRRMGDRRAGPNS | ||||||
Compositional bias | 669-683 | Polar residues | ||||
Sequence: RPVSRSGSQDSVGSV | ||||||
Region | 741-826 | Disordered | ||||
Sequence: IDGNYMRESHSAENTPPTMRRSQTNPTLRDAANLPPRINNYMKNGQQFSPRHSIAGDTHLAQRLGQQQPTQQQQQQQTQQSPNEGQ | ||||||
Compositional bias | 748-770 | Polar residues | ||||
Sequence: ESHSAENTPPTMRRSQTNPTLRD | ||||||
Compositional bias | 779-793 | Polar residues | ||||
Sequence: NNYMKNGQQFSPRHS | ||||||
Compositional bias | 800-826 | Polar residues | ||||
Sequence: LAQRLGQQQPTQQQQQQQTQQSPNEGQ | ||||||
Region | 886-905 | Disordered | ||||
Sequence: PAQNAQSMKSPPHKANSQYS | ||||||
Region | 946-966 | Disordered | ||||
Sequence: QESGANEDEEADNTVIHQEQD | ||||||
Compositional bias | 948-966 | Basic and acidic residues | ||||
Sequence: SGANEDEEADNTVIHQEQD | ||||||
Region | 994-1057 | Disordered | ||||
Sequence: TGIGKEDKPKTPQTKANPESKQYPSHFTESHSSKSTEHQTSSTVVRGKQTESAANIQNNNVSRV | ||||||
Compositional bias | 1008-1057 | Polar residues | ||||
Sequence: KANPESKQYPSHFTESHSSKSTEHQTSSTVVRGKQTESAANIQNNNVSRV | ||||||
Region | 1062-1081 | Disordered | ||||
Sequence: PQPSLYSYNDNVTASPGSEK | ||||||
Region | 1132-1172 | Disordered | ||||
Sequence: LETTNRQTGGTPMRPDSHNRSLNATNGSIGSGTNTPSHHKS | ||||||
Compositional bias | 1220-1238 | Polar residues | ||||
Sequence: VVSPSELPDSPSDSMPGSP | ||||||
Region | 1220-1356 | Disordered | ||||
Sequence: VVSPSELPDSPSDSMPGSPSRKSPVKFDSKLNDSQSTNITQIRKPVVQQQPPPPANISAAGEESNVQIVRPIPTKTLFADSPKQFGDEGTPDFSCATSLSGLDLDEPDICRDSELERIPLGPEEGEEEAPSSGEPSQ | ||||||
Compositional bias | 1248-1265 | Polar residues | ||||
Sequence: SKLNDSQSTNITQIRKPV | ||||||
Compositional bias | 1324-1343 | Basic and acidic residues | ||||
Sequence: DEPDICRDSELERIPLGPEE | ||||||
Region | 1467-1494 | Disordered | ||||
Sequence: NLGGLGERESPTNDDDDKSDISSIADDG | ||||||
Region | 1510-1560 | Disordered | ||||
Sequence: PKKVAKASKSDNRTAKGQMERPKEGALVKEKHQQQNMRQHSQQQVYPQRGS | ||||||
Compositional bias | 1515-1545 | Basic and acidic residues | ||||
Sequence: KASKSDNRTAKGQMERPKEGALVKEKHQQQN | ||||||
Region | 1598-1656 | Disordered | ||||
Sequence: SELSQLDPDGASQDHSVGSELDESDQFDEIPTAYFDGDTSLPVEIMDSPTSFGMEGTPL | ||||||
Region | 1685-1746 | Disordered | ||||
Sequence: AKLPLHSKGSPKSLLTPKQRLLGRLKSPGSGSKNRSPGSRAQRNLAFGKPQPQSPLAMSPPR | ||||||
Compositional bias | 1713-1733 | Polar residues | ||||
Sequence: GSGSKNRSPGSRAQRNLAFGK | ||||||
Region | 1861-1941 | Disordered | ||||
Sequence: KTKSAKKKVSKIPRNCPTSTPKDKFVKPRTPPSGNQPKVKTPSPSREGSPKNVQSSQHGNEVERTRVEEQNTSEHPQLTIE | ||||||
Compositional bias | 1894-1920 | Polar residues | ||||
Sequence: GNQPKVKTPSPSREGSPKNVQSSQHGN | ||||||
Compositional bias | 2115-2146 | Polar residues | ||||
Sequence: MMSSVGDDNQVTVRSKSSTGASVRNVSNETDL | ||||||
Region | 2115-2186 | Disordered | ||||
Sequence: MMSSVGDDNQVTVRSKSSTGASVRNVSNETDLSLDEGVGHDDSNDTAIEDDDSKRFSDVTEGSDTNSHEITL | ||||||
Compositional bias | 2148-2186 | Basic and acidic residues | ||||
Sequence: LDEGVGHDDSNDTAIEDDDSKRFSDVTEGSDTNSHEITL | ||||||
Compositional bias | 2246-2266 | Polar residues | ||||
Sequence: SSKAMSEKTNEDSNASSSAAS | ||||||
Region | 2246-2856 | Disordered | ||||
Sequence: SSKAMSEKTNEDSNASSSAASRPRILKPGERSSLEVKAKEEEVKAVRGKRKPLTSRVNSGRPPSVSSPMKNDTKSKKTTPPTKPNTVKSKPPVGNTKVIPKTPSKVTPAAKSNVTPAAKAAPKMKPLAGKPTAGVKPTPKASAVVAPMTKNTNATRAAARKPSPARSGTASPRNQSPADKMRNKTTTKEPSSLASTNVKKPQSKVTSALIKGKAKNSGKVNNNEADRPKPPIKQGTFTKDSPTQNAPEIEGDDNEDIKDDSPSSNRSSAELKYSNDTQEKAPGEKISPRSSKADAAGPSSTPPAVANLKQNGSQKAVAGKSNSTGNLTKTTKSVTKTASGSNLTKTGSNTSLTKGSGTFKVPKAPLKKGDSMSNQSLKKDSSKPGTSVTTPKKGTGNDKTGGRATVPVASKIASLWRKGDSKTASPSKAGPEKKTPLKKEKEKTPAAKSETKPKFLRRSLASSQPSKGAKEDGKQSKTPNKKDDKGMQRSSTYDKLPVNEGEAESAEKAETSSGGSPAKNNVWRRTYTIENEEEVLQAVTTDDCETSNSPGVWMRRDNDRTPVKSQIPAPVRSSPEQSGDGRGNKPSPPSAFPNKSGLGISPPGAKPTVTS | ||||||
Compositional bias | 2273-2294 | Basic and acidic residues | ||||
Sequence: PGERSSLEVKAKEEEVKAVRGK | ||||||
Compositional bias | 2302-2337 | Polar residues | ||||
Sequence: VNSGRPPSVSSPMKNDTKSKKTTPPTKPNTVKSKPP | ||||||
Compositional bias | 2412-2449 | Polar residues | ||||
Sequence: SGTASPRNQSPADKMRNKTTTKEPSSLASTNVKKPQSK | ||||||
Compositional bias | 2538-2602 | Polar residues | ||||
Sequence: ADAAGPSSTPPAVANLKQNGSQKAVAGKSNSTGNLTKTTKSVTKTASGSNLTKTGSNTSLTKGSG | ||||||
Compositional bias | 2614-2641 | Polar residues | ||||
Sequence: GDSMSNQSLKKDSSKPGTSVTTPKKGTG | ||||||
Compositional bias | 2677-2700 | Basic and acidic residues | ||||
Sequence: EKKTPLKKEKEKTPAAKSETKPKF | ||||||
Compositional bias | 2715-2735 | Basic and acidic residues | ||||
Sequence: KEDGKQSKTPNKKDDKGMQRS | ||||||
Compositional bias | 2754-2770 | Polar residues | ||||
Sequence: AETSSGGSPAKNNVWRR | ||||||
Compositional bias | 2785-2799 | Polar residues | ||||
Sequence: TTDDCETSNSPGVWM | ||||||
Compositional bias | 2812-2829 | Polar residues | ||||
Sequence: IPAPVRSSPEQSGDGRGN | ||||||
Region | 2868-2903 | Disordered | ||||
Sequence: VPTQSLNNKPVSSANDENDLKGMKPNNGTDSPTRPM | ||||||
Region | 2917-2946 | Disordered | ||||
Sequence: YLNSVNKSGEEQKTSEEDESKRTACLVTTV |
Sequence similarities
Belongs to the adenomatous polyposis coli (APC) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,946
- Mass (Da)319,714
- Last updated2016-11-02 v1
- ChecksumCD882A584B5D088F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 252-266 | Basic and acidic residues | ||||
Sequence: ENQDSNKKATGHGSA | ||||||
Compositional bias | 669-683 | Polar residues | ||||
Sequence: RPVSRSGSQDSVGSV | ||||||
Compositional bias | 748-770 | Polar residues | ||||
Sequence: ESHSAENTPPTMRRSQTNPTLRD | ||||||
Compositional bias | 779-793 | Polar residues | ||||
Sequence: NNYMKNGQQFSPRHS | ||||||
Compositional bias | 800-826 | Polar residues | ||||
Sequence: LAQRLGQQQPTQQQQQQQTQQSPNEGQ | ||||||
Compositional bias | 948-966 | Basic and acidic residues | ||||
Sequence: SGANEDEEADNTVIHQEQD | ||||||
Compositional bias | 1008-1057 | Polar residues | ||||
Sequence: KANPESKQYPSHFTESHSSKSTEHQTSSTVVRGKQTESAANIQNNNVSRV | ||||||
Compositional bias | 1220-1238 | Polar residues | ||||
Sequence: VVSPSELPDSPSDSMPGSP | ||||||
Compositional bias | 1248-1265 | Polar residues | ||||
Sequence: SKLNDSQSTNITQIRKPV | ||||||
Compositional bias | 1324-1343 | Basic and acidic residues | ||||
Sequence: DEPDICRDSELERIPLGPEE | ||||||
Compositional bias | 1515-1545 | Basic and acidic residues | ||||
Sequence: KASKSDNRTAKGQMERPKEGALVKEKHQQQN | ||||||
Compositional bias | 1713-1733 | Polar residues | ||||
Sequence: GSGSKNRSPGSRAQRNLAFGK | ||||||
Compositional bias | 1894-1920 | Polar residues | ||||
Sequence: GNQPKVKTPSPSREGSPKNVQSSQHGN | ||||||
Compositional bias | 2115-2146 | Polar residues | ||||
Sequence: MMSSVGDDNQVTVRSKSSTGASVRNVSNETDL | ||||||
Compositional bias | 2148-2186 | Basic and acidic residues | ||||
Sequence: LDEGVGHDDSNDTAIEDDDSKRFSDVTEGSDTNSHEITL | ||||||
Compositional bias | 2246-2266 | Polar residues | ||||
Sequence: SSKAMSEKTNEDSNASSSAAS | ||||||
Compositional bias | 2273-2294 | Basic and acidic residues | ||||
Sequence: PGERSSLEVKAKEEEVKAVRGK | ||||||
Compositional bias | 2302-2337 | Polar residues | ||||
Sequence: VNSGRPPSVSSPMKNDTKSKKTTPPTKPNTVKSKPP | ||||||
Compositional bias | 2412-2449 | Polar residues | ||||
Sequence: SGTASPRNQSPADKMRNKTTTKEPSSLASTNVKKPQSK | ||||||
Compositional bias | 2538-2602 | Polar residues | ||||
Sequence: ADAAGPSSTPPAVANLKQNGSQKAVAGKSNSTGNLTKTTKSVTKTASGSNLTKTGSNTSLTKGSG | ||||||
Compositional bias | 2614-2641 | Polar residues | ||||
Sequence: GDSMSNQSLKKDSSKPGTSVTTPKKGTG | ||||||
Compositional bias | 2677-2700 | Basic and acidic residues | ||||
Sequence: EKKTPLKKEKEKTPAAKSETKPKF | ||||||
Compositional bias | 2715-2735 | Basic and acidic residues | ||||
Sequence: KEDGKQSKTPNKKDDKGMQRS | ||||||
Compositional bias | 2754-2770 | Polar residues | ||||
Sequence: AETSSGGSPAKNNVWRR | ||||||
Compositional bias | 2785-2799 | Polar residues | ||||
Sequence: TTDDCETSNSPGVWM | ||||||
Compositional bias | 2812-2829 | Polar residues | ||||
Sequence: IPAPVRSSPEQSGDGRGN |