A0A1B1JCF4 · A0A1B1JCF4_SACKO
- ProteinDelta-1-pyrroline-5-carboxylate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids795 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- ATP + L-glutamate = ADP + L-glutamyl 5-phosphate
Pathway
Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.
Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | glutamate 5-kinase activity | |
Molecular Function | glutamate-5-semialdehyde dehydrogenase activity | |
Biological Process | L-proline biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDelta-1-pyrroline-5-carboxylate synthase
Including 2 domains:
- Recommended nameGlutamate 5-kinase
- EC number
- Short namesGK
- Alternative names
- Recommended nameGamma-glutamyl phosphate reductase
- EC number
- Short namesGPR
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Hemichordata > Enteropneusta > Harrimaniidae > Saccoglossus
Accessions
- Primary accessionA0A1B1JCF4
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 84-337 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: KKIVIKLGSAVLTRGDECGLALGRLASIIEQVAELQNAGYEMMVVTSGAVAFGKLRLRQEVLLSQSMRETLSNRADNKGQIMLEPRACAAAGQSGLMALYEAMFSQYGVTTAQVLVTKPDFYHDYTRNNLRGTINELVQMNIIPIINANDVVAPPPEKDKDLQGVISIKDNDSLAARVAVEMGAHLLIMLSDVNGIYTGPPGAEGSLLLHTFYPGDSTNIVYGAKSRVGLGGMESKVKAAQWALDRGTSVVIAN | ||||||
Domain | 374-667 | Aldehyde dehydrogenase | ||||
Sequence: NARDGGRDLLALTADQRADIINRLAELLIERQDKILSENKKDLELSRRQGDLTPPMLARLSLSPTKLRSLSDGLRQIAASSHNNVGRIVKKTKIADGMELTQETVPIGVLLVIFESRPDALPQVAALAISSANGLLLKGGKEAANSNAYLHSLVQEALSIHAPKDAVQLVETREEVNDLLELDDLIDLVIPRGSNELVRKIQNESKGIPVLGHSEGICHVFIDKAADPQMAIKLVRDSKCDYPAACNAMETLLIHQDHRHTKLFEDILDMLKAEHVKFHPGPRLAKSLKFGPSE |
Sequence similarities
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
In the N-terminal section; belongs to the glutamate 5-kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length795
- Mass (Da)86,492
- Last updated2016-11-02 v1
- Checksum664D9603131DEC1E