A0A1B0GW91 · A0A1B0GW91_HUMAN

  • Protein
    Transcription factor 4
  • Gene
    TCF4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionprotein dimerization activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription factor 4

Gene names

    • Name
      TCF4

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A1B0GW91

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 685 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)81PRIDEPhosphothreonine
Modified residue (large scale data)96PRIDEPhosphoserine
Modified residue (large scale data)101PRIDEPhosphoserine
Modified residue (large scale data)102PRIDEPhosphoserine
Modified residue (large scale data)117PRIDEPhosphoserine
Modified residue (large scale data)124PRIDEPhosphoserine
Modified residue (large scale data)126PRIDEPhosphoserine
Modified residue (large scale data)127PRIDEPhosphoserine
Modified residue (large scale data)131PRIDEPhosphothreonine
Modified residue (large scale data)135PRIDEPhosphoserine
Modified residue (large scale data)154PRIDEPhosphoserine
Modified residue (large scale data)155PRIDEPhosphoserine
Modified residue (large scale data)156PRIDEPhosphoserine
Modified residue (large scale data)159PRIDEPhosphotyrosine
Modified residue (large scale data)267PRIDEPhosphothreonine
Modified residue (large scale data)268PRIDEPhosphoserine
Modified residue (large scale data)294PRIDEPhosphoserine
Modified residue (large scale data)299PRIDEPhosphoserine
Modified residue (large scale data)333PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-42Polar residues
Region1-105Disordered
Compositional bias51-103Polar residues
Region120-163Disordered
Region250-358Disordered
Compositional bias253-272Polar residues
Compositional bias297-358Basic and acidic residues
Domain352-405BHLH
Region422-455Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    455
  • Mass (Da)
    48,584
  • Last updated
    2016-10-05 v1
  • Checksum
    CBBB0CBE9630F7EE
MQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM

Computationally mapped potential isoform sequences

There are 48 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P15884ITF2_HUMANTCF4667
A0A075B723A0A075B723_HUMANTCF4209
G0LNT4G0LNT4_HUMANTCF4139
G0LNT7G0LNT7_HUMANTCF4119
A0A0E3D6N2A0A0E3D6N2_HUMANTCF465
A0A6Q8PGE3A0A6Q8PGE3_HUMANTCF464
H3BUQ3H3BUQ3_HUMANTCF4146
H3BTP3H3BTP3_HUMANTCF4677
H3BTM9H3BTM9_HUMANTCF4134
H3BTZ0H3BTZ0_HUMANTCF4280
H3BT24H3BT24_HUMANTCF4287
H3BTC3H3BTC3_HUMANTCF4158
H3BT95H3BT95_HUMANTCF4168
H3BRF7H3BRF7_HUMANTCF4179
H3BPG3H3BPG3_HUMANTCF4162
H3BPJ7H3BPJ7_HUMANTCF4642
H3BP59H3BP59_HUMANTCF4165
H3BNI2H3BNI2_HUMANTCF456
H3BNZ2H3BNZ2_HUMANTCF4163
H3BMC8H3BMC8_HUMANTCF4135
H3BME8H3BME8_HUMANTCF4124
H3BML7H3BML7_HUMANTCF461
A0A1B0GVB8A0A1B0GVB8_HUMANTCF4631
A0A1B0GUT3A0A1B0GUT3_HUMANTCF450
A0A1B0GV10A0A1B0GV10_HUMANTCF499
A0A1B0GTP2A0A1B0GTP2_HUMANTCF4102
A0A1B0GXH5A0A1B0GXH5_HUMANTCF4118
A0A1B0GWD5A0A1B0GWD5_HUMANTCF4541
A0A1B0GVR6A0A1B0GVR6_HUMANTCF4680
A0A0D9SEK1A0A0D9SEK1_HUMANTCF4224
A0A0D9SF18A0A0D9SF18_HUMANTCF4202
A0A0D9SGH7A0A0D9SGH7_HUMANTCF481
A0A0D9SGJ4A0A0D9SGJ4_HUMANTCF4134
A0A0D9SG78A0A0D9SG78_HUMANTCF4315
A0A0D9SFX5A0A0D9SFX5_HUMANTCF4228
A0A0D9SFZ1A0A0D9SFZ1_HUMANTCF480
A0A0D9SGE4A0A0D9SGE4_HUMANTCF4135
A0A0D9SGE5A0A0D9SGE5_HUMANTCF4221
A0A0D9SGE7A0A0D9SGE7_HUMANTCF4128
A0A0D9SG44A0A0D9SG44_HUMANTCF481
A0A0D9SFU5A0A0D9SFU5_HUMANTCF4207
A0A0D9SG55A0A0D9SG55_HUMANTCF4156
A0A0D9SG61A0A0D9SG61_HUMANTCF4204
A0A0D9SEX8A0A0D9SEX8_HUMANTCF4179
A0A0D9SEZ3A0A0D9SEZ3_HUMANTCF4236
A0A0D9SF97A0A0D9SF97_HUMANTCF4155
E9PH57E9PH57_HUMANTCF4773
K7ESI6K7ESI6_HUMANTCF4166

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-42Polar residues
Compositional bias51-103Polar residues
Compositional bias253-272Polar residues
Compositional bias297-358Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC013587
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC018994
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC090383
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC090684
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC091103
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
KF459816
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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