A0A1B0GU48 · A0A1B0GU48_HUMAN

  • Protein
    Euchromatic histone lysine methyltransferase 1
  • Gene
    EHMT1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnuclear body
Cellular Componentnucleoplasm
Molecular Functionhistone methyltransferase activity
Molecular Functionp53 binding
Molecular Functionprotein-lysine N-methyltransferase activity
Molecular Functionzinc ion binding

Names & Taxonomy

Protein names

  • Submitted names
    • Euchromatic histone lysine methyltransferase 1

Gene names

    • Name
      EHMT1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A1B0GU48

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)133PRIDEPhosphothreonine
Modified residue (large scale data)345PRIDEPhosphoserine
Modified residue (large scale data)395PRIDEPhosphothreonine
Modified residue (large scale data)397PRIDEPhosphoserine
Modified residue (large scale data)445PRIDEPhosphoserine
Modified residue (large scale data)614PRIDEPhosphothreonine
Modified residue (large scale data)670PRIDEPhosphothreonine
Modified residue (large scale data)960PRIDEPhosphoserine
Modified residue (large scale data)966PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias, domain, repeat.

Type
IDPosition(s)Description
Region1-82Disordered
Compositional bias23-63Polar residues
Region113-162Disordered
Region180-203Disordered
Compositional bias185-203Basic and acidic residues
Region285-441Disordered
Compositional bias307-323Acidic residues
Compositional bias339-357Basic and acidic residues
Compositional bias358-377Acidic residues
Compositional bias419-439Polar residues
Domain502-595EHMT1/2 cysteine-rich region
Region606-679Disordered
Repeat734-766ANK
Repeat767-799ANK
Repeat800-824ANK
Repeat834-866ANK
Repeat900-932ANK
Region958-981Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    981
  • Mass (Da)
    105,883
  • Last updated
    2016-10-05 v1
  • Checksum
    4BE9027384E68826
MAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKGSALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRPSPVERIVSRDIARGYE

Computationally mapped potential isoform sequences

There are 22 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9H9B1EHMT1_HUMANEHMT11298
A0A1B0GV89A0A1B0GV89_HUMANEHMT1112
A0A1B0GV09A0A1B0GV09_HUMANEHMT11267
A0A1B0GUD1A0A1B0GUD1_HUMANEHMT1556
A0A1B0GTP4A0A1B0GTP4_HUMANEHMT1153
A0A1B0GWF6A0A1B0GWF6_HUMANEHMT1370
A0A1B0GW79A0A1B0GW79_HUMANEHMT1277
A0A1B0GVZ8A0A1B0GVZ8_HUMANEHMT1543
A0A1B0GW12A0A1B0GW12_HUMANEHMT1126
A0A1W2PPZ7A0A1W2PPZ7_HUMANEHMT1394
A0A0D9SEQ1A0A0D9SEQ1_HUMANEHMT1432
A0A0D9SEP2A0A0D9SEP2_HUMANEHMT1106
A0A0D9SER3A0A0D9SER3_HUMANEHMT1137
A0A0D9SER9A0A0D9SER9_HUMANEHMT1230
A0A0D9SF38A0A0D9SF38_HUMANEHMT1167
A0A0D9SFX4A0A0D9SFX4_HUMANEHMT1268
A0A0D9SFG7A0A0D9SFG7_HUMANEHMT1139
A0A0D9SFM6A0A0D9SFM6_HUMANEHMT1117
A0A0D9SFS4A0A0D9SFS4_HUMANEHMT1134
A0A0D9SEY2A0A0D9SEY2_HUMANEHMT1108
A0A0D9SFD7A0A0D9SFD7_HUMANEHMT1107
A0A0C4DGF8A0A0C4DGF8_HUMANEHMT1803

Features

Showing features for compositional bias, non-terminal residue.

Type
IDPosition(s)Description
Compositional bias23-63Polar residues
Compositional bias185-203Basic and acidic residues
Compositional bias307-323Acidic residues
Compositional bias339-357Basic and acidic residues
Compositional bias358-377Acidic residues
Compositional bias419-439Polar residues
Non-terminal residue981

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL365502
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL590627
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL611925
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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