A0A1B0GTS4 · A0A1B0GTS4_HUMAN
- ProteinCalcium voltage-gated channel auxiliary subunit beta 4
- GeneCACNB4
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids411 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | voltage-gated calcium channel complex | |
Molecular Function | voltage-gated calcium channel activity |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionA0A1B0GTS4
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 489 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-25 | Disordered | ||||
Sequence: MAGSADSYTSRPSDSDVSLEEDREA | ||||||
Domain | 45-114 | SH3 | ||||
Sequence: PVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIR | ||||||
Region | 119-138 | Disordered | ||||
Sequence: QKRGRFHGGKSSGNSSSSLG | ||||||
Region | 322-411 | Disordered | ||||
Sequence: QCPPSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL | ||||||
Compositional bias | 326-346 | Polar residues | ||||
Sequence: SQRMRHSNHSTENSPIERRSL | ||||||
Compositional bias | 347-392 | Basic and acidic residues | ||||
Sequence: MTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK |
Sequence similarities
Belongs to the calcium channel beta subunit family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length411
- Mass (Da)46,319
- Last updated2016-10-05 v1
- Checksum72052E5D302D185C
Computationally mapped potential isoform sequences
There are 46 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
O00305 | CACB4_HUMAN | CACNB4 | 520 | ||
C9J224 | C9J224_HUMAN | CACNB4 | 125 | ||
A0A1B0GVB2 | A0A1B0GVB2_HUMAN | CACNB4 | 393 | ||
A0A1B0GUU5 | A0A1B0GUU5_HUMAN | CACNB4 | 40 | ||
A0A1B0GUU8 | A0A1B0GUU8_HUMAN | CACNB4 | 194 | ||
A0A1B0GUW8 | A0A1B0GUW8_HUMAN | CACNB4 | 215 | ||
A0A1B0GUK3 | A0A1B0GUK3_HUMAN | CACNB4 | 202 | ||
A0A1B0GUK4 | A0A1B0GUK4_HUMAN | CACNB4 | 392 | ||
A0A1B0GUM9 | A0A1B0GUM9_HUMAN | CACNB4 | 334 | ||
A0A1B0GUR1 | A0A1B0GUR1_HUMAN | 44 | |||
A0A1B0GV16 | A0A1B0GV16_HUMAN | CACNB4 | 307 | ||
A0A1B0GUI5 | A0A1B0GUI5_HUMAN | CACNB4 | 307 | ||
A0A1B0GUI8 | A0A1B0GUI8_HUMAN | CACNB4 | 256 | ||
A0A1B0GUJ7 | A0A1B0GUJ7_HUMAN | CACNB4 | 145 | ||
A0A1B0GU32 | A0A1B0GU32_HUMAN | CACNB4 | 158 | ||
A0A1B0GU42 | A0A1B0GU42_HUMAN | CACNB4 | 80 | ||
A0A1B0GU53 | A0A1B0GU53_HUMAN | CACNB4 | 424 | ||
A0A1B0GTX2 | A0A1B0GTX2_HUMAN | CACNB4 | 490 | ||
A0A1B0GTX6 | A0A1B0GTX6_HUMAN | CACNB4 | 180 | ||
A0A1B0GTX8 | A0A1B0GTX8_HUMAN | CACNB4 | 410 | ||
A0A1B0GTK1 | A0A1B0GTK1_HUMAN | CACNB4 | 423 | ||
A0A1B0GTL1 | A0A1B0GTL1_HUMAN | CACNB4 | 48 | ||
A0A1B0GTN2 | A0A1B0GTN2_HUMAN | CACNB4 | 110 | ||
A0A1B0GTN8 | A0A1B0GTN8_HUMAN | CACNB4 | 461 | ||
A0A1B0GTP5 | A0A1B0GTP5_HUMAN | CACNB4 | 334 | ||
A0A1B0GU05 | A0A1B0GU05_HUMAN | CACNB4 | 323 | ||
A0A1B0GU07 | A0A1B0GU07_HUMAN | CACNB4 | 113 | ||
A0A1B0GTA9 | A0A1B0GTA9_HUMAN | CACNB4 | 452 | ||
A0A1B0GTP6 | A0A1B0GTP6_HUMAN | CACNB4 | 363 | ||
A0A1B0GTF6 | A0A1B0GTF6_HUMAN | CACNB4 | 445 | ||
A0A1B0GTH0 | A0A1B0GTH0_HUMAN | CACNB4 | 232 | ||
A0A1B0GXG0 | A0A1B0GXG0_HUMAN | CACNB4 | 472 | ||
A0A1B0GWG5 | A0A1B0GWG5_HUMAN | CACNB4 | 194 | ||
A0A1B0GWF9 | A0A1B0GWF9_HUMAN | CACNB4 | 341 | ||
A0A1B0GW81 | A0A1B0GW81_HUMAN | CACNB4 | 38 | ||
A0A1B0GVP7 | A0A1B0GVP7_HUMAN | CACNB4 | 79 | ||
A0A1B0GVT6 | A0A1B0GVT6_HUMAN | CACNB4 | 219 | ||
A0A1B0GVU5 | A0A1B0GVU5_HUMAN | CACNB4 | 407 | ||
A0A1B0GW58 | A0A1B0GW58_HUMAN | CACNB4 | 124 | ||
A0A1B0GW63 | A0A1B0GW63_HUMAN | CACNB4 | 272 | ||
A0A1B0GVF0 | A0A1B0GVF0_HUMAN | CACNB4 | 351 | ||
A0A1B0GVG1 | A0A1B0GVG1_HUMAN | CACNB4 | 168 | ||
H0Y476 | H0Y476_HUMAN | CACNB4 | 473 | ||
A0A1C7CYX2 | A0A1C7CYX2_HUMAN | CACNB4 | 479 | ||
E7DBM8 | E7DBM8_HUMAN | CACNB4 | 207 | ||
E7EN11 | E7EN11_HUMAN | CACNB4 | 441 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 326-346 | Polar residues | ||||
Sequence: SQRMRHSNHSTENSPIERRSL | ||||||
Compositional bias | 347-392 | Basic and acidic residues | ||||
Sequence: MTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC068547 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC079790 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC097448 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |