A0A1B0GSI7 · A0A1B0GSI7_MOUSE
- ProteinCollagen, type IV, alpha 1
- GeneCol4a1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1562 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | basement membrane | |
Cellular Component | collagen trimer | |
Cellular Component | membrane | |
Molecular Function | extracellular matrix structural constituent |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A1B0GSI7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-25 | ||||
Chain | PRO_5008408587 | 26-1562 | |||
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 47-1443 | Disordered | |||
Compositional bias | 109-123 | Pro residues | |||
Compositional bias | 140-154 | Pro residues | |||
Compositional bias | 191-215 | Pro residues | |||
Compositional bias | 281-299 | Basic and acidic residues | |||
Compositional bias | 363-380 | Pro residues | |||
Compositional bias | 409-425 | Pro residues | |||
Compositional bias | 788-817 | Pro residues | |||
Compositional bias | 1245-1259 | Pro residues | |||
Compositional bias | 1341-1374 | Pro residues | |||
Compositional bias | 1415-1434 | Pro residues | |||
Domain | 1445-1546 | Collagen IV NC1 | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,562
- Mass (Da)149,165
- Last updated2016-10-05 v1
- ChecksumF17755123A2CC87D
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P02463 | CO4A1_MOUSE | Col4a1 | 1669 | ||
A0A1B0GT69 | A0A1B0GT69_MOUSE | Col4a1 | 126 | ||
A0A1B0GRC0 | A0A1B0GRC0_MOUSE | Col4a1 | 328 | ||
A0A140LHU8 | A0A140LHU8_MOUSE | Col4a1 | 133 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 109-123 | Pro residues | |||
Compositional bias | 140-154 | Pro residues | |||
Compositional bias | 191-215 | Pro residues | |||
Compositional bias | 281-299 | Basic and acidic residues | |||
Compositional bias | 363-380 | Pro residues | |||
Compositional bias | 409-425 | Pro residues | |||
Compositional bias | 788-817 | Pro residues | |||
Compositional bias | 1245-1259 | Pro residues | |||
Compositional bias | 1341-1374 | Pro residues | |||
Compositional bias | 1415-1434 | Pro residues | |||
Keywords
- Technical term