A0A1B0GRU0 · A0A1B0GRU0_MOUSE
- ProteinVesicular glutamate transporter 1
- GeneSlc17a7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids585 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- 3 Na+(out) + phosphate(out) = 3 Na+(in) + phosphate(in)
3 Na+ (out)CHEBI:29101+ phosphate (out)CHEBI:43474= 3 Na+ (in)CHEBI:29101+ phosphate (in)CHEBI:43474 - H+(out) + K+(in) = H+(in) + K+(out)
- L-glutamate(out) = L-glutamate(in)
- chloride(in) = chloride(out)
- phosphate(in) = phosphate(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloride channel complex | |
Cellular Component | excitatory synapse | |
Cellular Component | neuron projection | |
Cellular Component | plasma membrane | |
Cellular Component | presynaptic active zone | |
Cellular Component | synaptic vesicle membrane | |
Molecular Function | chloride channel activity | |
Molecular Function | L-glutamate uniporter activity | |
Molecular Function | phosphate ion uniporter activity | |
Molecular Function | potassium:proton antiporter activity | |
Molecular Function | sodium:phosphate symporter activity | |
Biological Process | neural retina development | |
Biological Process | neurotransmitter loading into synaptic vesicle | |
Biological Process | phosphate ion homeostasis | |
Biological Process | regulation of synaptic vesicle endocytosis | |
Biological Process | sodium-dependent phosphate transport |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameVesicular glutamate transporter 1
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A1B0GRU0
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 231-256 | Helical | ||||
Sequence: LATTAFCGSYAGAVVAMPLAGVLVQY | ||||||
Transmembrane | 262-280 | Helical | ||||
Sequence: VFYVYGSFGIFWYLFWLLV | ||||||
Transmembrane | 329-353 | Helical | ||||
Sequence: VYAIIVANFCRSWTFYLLLISQPAY | ||||||
Transmembrane | 365-383 | Helical | ||||
Sequence: VGLVSALPHLVMTIIVPIG | ||||||
Transmembrane | 428-449 | Helical | ||||
Sequence: VAISFLVLAVGFSGFAISGFNV | ||||||
Transmembrane | 461-481 | Helical | ||||
Sequence: ILMGISNGVGTLSGMVCPIIV | ||||||
Transmembrane | 493-514 | Helical | ||||
Sequence: WQYVFLIASLVHYGGVIFYGVF |
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 62-519 | Major facilitator superfamily (MFS) profile | ||||
Sequence: RYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQEAVTPTLGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEK | ||||||
Region | 522-585 | Disordered | ||||
Sequence: WAEPEEMSEEKCGFVGHDQLAGSDESEMEDEAEPPGAPPAPPPSYGATHSTVQPPRPPPPVRDY |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length585
- Mass (Da)64,319
- Last updated2016-10-05 v1
- ChecksumB75905A680D02363
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q3TXX4 | VGLU1_MOUSE | Slc17a7 | 560 |
Keywords
- Technical term