A0A1B0CX01 · A0A1B0CX01_LUTLO
- Proteinaconitate hydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1039 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Catalytic activity
- citrate = D-threo-isocitrate
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | aconitate hydratase activity | |
Molecular Function | metal ion binding | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameaconitate hydratase
- EC number
- Alternative names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Nematocera > Psychodoidea > Psychodidae > Lutzomyia > Lutzomyia
Accessions
- Primary accessionA0A1B0CX01
Proteomes
Organism-specific databases
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 123-147 | HIT-type | ||||
Sequence: RHFCAVCGFPSNYTCTSCGTRMSYC | ||||||
Domain | 308-745 | Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha | ||||
Sequence: EKVLYSHLDDPQNQEIQRGVSYLRLRPDRVAMQDATAQMAMLQFISSGLKRVAVPSTIHCDHLIEAQIGGEQDLKRAKDINAEVYKFLSTAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPNVIGVHLTGKISGWTSPKDVILKVADILTVKGGTGAIIEYHGKGVDSISCTGMATICNMGAEIGATTSIFPFNNRMASYLKSTGRAGIATEATKFQGKLLSPDHGCKYDDVIEINLDKLEPHVNGPFTPDLAHPISKLGENSKKNGYPMDIRVGLIGSCTNSSYEDMGRCAAIAKDALAHGIKSKIPFNVTPGSEQIRATIERDGIAETFRQFGGTVLANACGPCIGQWDRKDVKKGEKNTIVTSYNRNFTGRNDANPATHCFVTSPELVTALSIAG | ||||||
Domain | 824-953 | Aconitase A/isopropylmalate dehydratase small subunit swivel | ||||
Sequence: MTVLIKVKGKCTTDHISAAGPWLKYRGHLDNISNNMFIGAVNSENSEMNKIKNQVTGEWGGVPDVARFYKSKGIKWVAVGDENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGLLPLTFAD |
Sequence similarities
Belongs to the aconitase/IPM isomerase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,039
- Mass (Da)114,103
- Last updated2016-10-05 v1
- Checksum77CB3A8B6B66AAF5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJWK01033078 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJWK01033079 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJWK01033080 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJWK01033081 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJWK01033082 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJWK01033083 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJWK01033084 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |