A0A1A8W5B0 · A0A1A8W5B0_9APIC

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Pathway

Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.

GO annotations

AspectTerm
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Functionglutamate synthase activity
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
Biological Processglutamine metabolic process
Biological ProcessL-glutamate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamate synthase (NADH)
  • EC number

Gene names

    • ORF names
      POVCU2_0041370

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Plasmodium)

Accessions

  • Primary accession
    A0A1A8W5B0

Proteomes

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain20-567Glutamine amidotransferase type-2
Region1157-1182Disordered
Region1555-1640Disordered
Compositional bias1562-1619Acidic residues
Compositional bias2728-2757Polar residues
Region2728-2771Disordered

Sequence similarities

Belongs to the glutamate synthase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,936
  • Mass (Da)
    331,606
  • Last updated
    2016-10-05 v1
  • Checksum
    4547F0246271E1B6
MKKDKGQHGLYDSRNEKDACGVGVVADINGKSSRNVIQKAMQILLRLSHRGGVQSNNGDGAGILVGIPHDYFQMLSDTCQLPFLLPERGDYAVAQIYLPQNEERRLFLYHEIEREVYNHGLVVLGWRSPIPVRSDVISATVKKSEPFIAQMFVCKRSVFKNYDDFNIYPFSDINFTDDRNLKLNDLPDDIELLSFFIRKKLVRHNDMYFCSFSSRTIVYKGLLTPSQIYLYFEDLLSEQFTTYLAMVHVRFSTNTSPTWYAAHPFRRICHNGEINTISVNTLLFKERMHLAKSPSFFKSVSIKDLKPINEENYIIYDNDDEIIQKRDTFEDIMLTKNRLKKKSRRNLLLKLKRDYTYNSSALHYKIKREYINSDINNSNSEILSNLNEISKSSSDDIMDVSEENEMYTYRDKSNQRDVGKNEIKTHLIYGESKKTKGAISFPSDSSIFDNAIDFLTMTGREIEHAVMMLMPRAYQKDPNISPLEKAFYEYHTCLMEPWDGPALIIFTDGNKVGASLDRNGLRPARYSITNYGLFVLSSETGVVDLPYDKITHQGCVYPGKVVLVDFKEKAFLRHEEVLSKFLKLYPYKKWLDHYSIHLDHIIKPASNMENIRMNAYKYGTILNKENYYNKKETDVDYHDESLIKKLKAFGYTYDAFNMIISPMVKHAADGLGAMGNDTAFPFLSYLRRNLLYYFQQTFAQVTNPAIDPIREENIMSLMSNLGKEGDLLHCTYNNCQRIFINGPILNEALYNMLLQLPDFPHIIIDMTVDVAKLESLMSGEEPNGDIKFDIIKGGSSPKRQYITEYSFTLDDKNKKRMNNGKETKEETSRKKIPSRYLIKFIDNVNAKVENAVRKGCQLIILSHGNVSNSRVPIFSILIVGALHKHLLSKNLRTKCSLIVKAGDCFEIHHLAVLLSFGADCIYPFILYESLQFIKYGDNEARLSNHQMVSNYRHAANYGILKIMSKNGISTLPSYKGCGLMQPLGISDEILKKCFINVCDSIIGGVTFEFIEKEILKIFNNAYPKRILTLNVKDATEELEDYGEYHFRSIGNAQIHLNHPETISLLQKATRTGNIDTYKKYTELQNELINHCEIRGQLEINYKKCPSYNKKKKKNEPININLVESVNKILLRFCTGAMSFGSLSEEAHTTVATAMNSMGLKSNTGEGGEAEERIKPPSNEANTNSAVKQIASARFGVTAYSLVNAQELQIKVAQGSKPGEGGELPGYKVNAKIASVRRSTPGVGLISPPPHHDMYSIEDVGQLVYDLKNINKEAKISVKLVSKLGIGVISSGVVKGNCEQILISGTSGGTGASKWTSIKHAGLPWEIGLAEAHQTLCKSKLRKRVILQIDGQLKTGRDVILGALLGAESFSFSTQPLIALGCIMMRKCHLNICPVGICTQDPELRKKFAGKPEYVVNFFFMLAEEVREYLASMGFRKFSHIIGRSDLLKKKDHLKYDEKRKLLDFSKLLFPGWKYYAEEEMKDATEKRYCGKSSGGGGGKKRVIANSRHAQFHNANLNVMSRIRRKQVLINENFNTVKNYDVSGEVSGVQRAVTACHEESVTYEGEDADDADEEGEDEEEEEDEEEEEDEEEEEEEDEEEEEEVEDEEEEEEEETELGEGRSEGEENREMLEKGTFLANGELTLRRRNRNEEVNLLGDDQKHGMVMTMTMNGREAKTPIKLLRKKLIEKKSHGKKKKMKPMAIFCCETQNHKLCDIIDRELIRRSKIALLNCTPVNIKMPIKNTDRAVGAMLSYHIIQKYGEEGLPMDTISVKFRGTGGLSFGVFLTTGVNFELEGDANDFVGKGLSGGIISVHFPKTSSFINDCQKNMIAGNSVLYGATKGRAFFAGRAGERFAVRNSGAIAVVEGVGCHGCEYMTKGIVVVLGEIGCNFAAGMSGGIAYVLDINEKNVNHQMVDLKICKTVDEKMTLEKLLHEHYERTNSYTAKMLLNNLDENLQRFTKIIPRDIKRVLTEACIEFVKTGNEEAAAILDDWASLLKSVDQPENMYKKAMQFFTTISDDIAGLSKTLALRNVDGLIIYDILRDNHSRKIISQTKGSSILGTSFIEEKMELHNEEQNFRRKRGFDFERFTHHLELCRKNNRKWRRYAEIPFKCNAFADFKSSFPLSLDEKAKEMIKKYMLNEKYLLDLHLKSLNSNSFIERLMNREESDDYMNMHQKEISPNICSLKKFLCSSDKNVSVQGEKAVKMDPNNSSNVNPEFIITPMYSTQNGNYVNMIDCNKNESSINVSGTHVAVTHRTSNKLVKNVQCSNENEIGDTSKVLVEYGNGHNSSQAKPFLVSNPNKVTGFIEYERLSHPLKDISTRVLDYSEIIVPVNVKSKLHNQLLKTQASRCVDCGTPTCHYPNSNGGGCPLGNRIFDWNNLIYENEWKKALERLLDTNNFPEITGRICPAPCEDACILSLNEKPVSIKFIELSIIECGFIKKWVQPIIPLFRTGKKVAIVGSGPAGLTAAQQLNKAGHEVTIFEKDEYFGGLLTNGIPNVRLDKKIIERRLILMKKEGIIMKNNINIGKDISLSELTKQFDAILLATGYKIPRTLDIPGSNLNNIFFAMDFLTSCQKSLTKSDLMDENYIDVSEKHVIILGGGKTAVDCISLAIRMGAASVLQFTRQEIAPVNTTNCSWPGIKNIFKVEYSHEEAIIIQGRDPREYCVRSIEFIPSSKDPKRVSGIRAIKVKVRKASKAGIGYAQAKSTVTLAATSVATSEVTSEITPVVTPGGTATSDGNAATGSSSTANPNHGCSKVRTKSKKPHGKTNKLKCQKNLMKQNYQETTTASSYSSSTIAENDLMKTYQMLKDNKEYVDVPFTERIYKADVVILALGFYKTDDSIWEEDKIKIELDKYNCIKTNERIYQTNRKNIFACGDCRIGPSTVVQAIAEGRDVAAKIDEFLTNSFSILPTCNTYDYYPRNYKNARFGSAHWG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1562-1619Acidic residues
Compositional bias2728-2757Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FLQU01000551
EMBL· GenBank· DDBJ
SBS87190.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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