A0A1A8VSR8 · A0A1A8VSR8_9APIC

  • Protein
    Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

Catalytic activity

Features

Showing features for binding site, active site.

160750100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site75S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site77S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site149S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site165S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site216S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site256Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctiontRNA (cytidine(32)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (guanine(34)-2'-O)-methyltransferase activity
Biological Processcytoplasmic translation
Biological ProcesstRNA nucleoside ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • 2'-O-ribose RNA methyltransferase TRM7 homolog

Gene names

    • ORF names
      POVCU1_011660
      , POVCU2_0012490

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Plasmodium)

Accessions

  • Primary accession
    A0A1A8VSR8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain21-81Ribosomal RNA methyltransferase FtsJ
Domain141-299Ribosomal RNA methyltransferase FtsJ
Compositional bias354-371Basic and acidic residues
Region354-373Disordered
Region381-462Disordered
Compositional bias389-403Basic and acidic residues
Compositional bias413-427Basic and acidic residues
Compositional bias441-455Basic and acidic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    69,542
  • Last updated
    2016-10-05 v1
  • Checksum
    A245BBFB0D279B4F
MGKLSKDRRDIYYRKAKENGYRARSSYKLIQINEKFEIFKLFNLNNYSNKDISDLIDIYNNRYCYNIVDLCAAPGSWSQVLKNICLYNYYQILHFLNKKNYEKSEYVEDEQFVKNFSLYINFNDALEEKIKNMNKYEAQVREPKMVAVDLQEIGNMGYVQIIQGDITKGSTIDRILKCMEGGNACNEGNARCRKDGVSYLDRKDCRVHYAHAVVSDGAPDITGMNDIDEFIQSQLILSSLKVCCSVLKIGGNFISKIFRGEHTGLLILHLNKFFERVYVCKPQSSRNKSLESFLVCLNFSLPLSNIIALDNHTEEQCPNYRKKTQRELREMHIQLIVNKDGDCKGGKRKGCMEKGGIGKKGESEENGECGLNRETGKISSTVGICTKGGDQRRESKTNDQGEGEYAEEEGDHCESEDSGKDAAENAEENASEGSGKYADGCPSDHTDKESSDEMSECENSFTPSEYKEKKIDMCVKNSGEKVHKGKDNNKKYINSCNEQNNEISVEGKITGKDEKRENLDIFNFYCSDSDEEIKYFNSEDEEIVNEYIASETFMNNKLFSFVATQNYYDSDKSYLLPQNYVRHEPQVMPLQPPYLLSLQKKRQEKKN

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias354-371Basic and acidic residues
Compositional bias389-403Basic and acidic residues
Compositional bias413-427Basic and acidic residues
Compositional bias441-455Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FLQU01000191
EMBL· GenBank· DDBJ
SBS81867.1
EMBL· GenBank· DDBJ
Genomic DNA
FLQV01000218
EMBL· GenBank· DDBJ
SBS84907.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp