A0A1A8DER7 · A0A1A8DER7_NOTKA

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Biological Processregulation of transcription by RNA polymerase II

Names & Taxonomy

Protein names

  • Submitted names
    • TSC22 domain family, member 2

Gene names

    • Name
      TSC22D2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Cyprinodontiformes > Nothobranchiidae > Nothobranchius

Accessions

  • Primary accession
    A0A1A8DER7

Structure

Select color scale


Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Source Identifier Method Resolution Chain Positions Links
AlphaFold AF-A0A1A8DER7-F1 Predicted 1-634 AlphaFold · Foldseek

3D structure databases

Family & Domains

Features

Showing features for region, compositional bias, coiled coil.

Type
IDPosition(s)Description
Region102-133Disordered
Compositional bias111-133Polar residues
Region218-266Disordered
Coiled coil547-581
Region614-634Disordered

Sequence similarities

Belongs to the TSC-22/Dip/Bun family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    634
  • Mass (Da)
    66,464
  • Last updated
    2016-10-05 v1
  • Checksum
    D6F2A61811C87DE9
MSKLAGKKKSCFQITSVTQAQVDASHVPDNTESMVYPDESRTEDLSSEVFDLSRVEQGVCDRSSPDETLNNVGDCQEGQIHNAGPVNGGISSTNTLTGRVTPHNAGGSVPGPAQPQASSSNTVPAASVAHTAPSSSCSSRFRVIKLDHGTGEPFRRGRWTCTEFYEKESDSSVNRTVDSIKPAVTHDQSIDRDSGLGVTSNFIVSSSVLANSTDSGFSVSAGHPTHSHTSDPLHQGYSLSPQIGSGASAFQPMGFTSTASQQTQQAHVNMQPITPQTFLPHGINGVHQGAMQQKPHIPLATQPQQVAYSTHPTGFSSSNPDYHQQHFGSGAQNVPSMTSPVGSSPPFTPACTRTQGFPVDVCSAQGLLQQVINAPVMPLILPGNPLQQPVNQTLPSGGLGVAPATSATITTCSHSGGQNVPATVPNTISIPPGVLSQVLNNGGNVQLQGALGGAAVGLFSGFSNQAEDSGQNSDVVPHQSATSVVPGKDGVLNLADESPTLVSPSVNSLFNIQIPIIEDDDSASGASIVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELYERNSVLERENAVLKSLANTEQLSHLSSQLSSSSAPMQLQQYPLVKNSTPALVHNEGGQSVPYQPNITSA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias111-133Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HAEA01003301
EMBL· GenBank· DDBJ
SBQ31781.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp