A0A1A2ANP2 · A0A1A2ANP2_9MYCO
- ProteinIsoprenyl transferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids262 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
Catalytic activity
- isopentenyl diphosphate + (2E)-geranyl diphosphate = (2Z,6E)-farnesyl diphosphate + diphosphate
Cofactor
Note: Binds 2 magnesium ions per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 40 | ||||
Binding site | 40 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 41-44 | substrate | |||
Binding site | 45 | substrate | |||
Binding site | 86-88 | substrate | |||
Active site | 89 | Proton acceptor | |||
Binding site | 92 | substrate | |||
Binding site | 211 | substrate | |||
Binding site | 217-219 | substrate | |||
Binding site | 230 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | magnesium ion binding | |
Molecular Function | polyprenyltransferase activity | |
Molecular Function | Z-farnesyl diphosphate synthase activity | |
Biological Process | polyprenol biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameIsoprenyl transferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionA0A1A2ANP2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Sequence
- Sequence statusComplete
- Length262
- Mass (Da)29,572
- Last updated2016-10-05 v1
- MD5 Checksum2B59EB7667D346ECE2B3EFB9B3BE97A3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LZIC01000054 EMBL· GenBank· DDBJ | OBF57154.1 EMBL· GenBank· DDBJ | Genomic DNA |