A0A198WZQ7 · A0A198WZQ7_MORCA

Function

function

Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.

Features

Showing features for binding site, active site, site.

Type
IDPosition(s)Description
Binding site93-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site11-121-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site203-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Active site45Proton acceptor
Binding site471-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site521-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Active site72Proton acceptor
Binding site1021-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Site152Transition state stabilizer
Active site196Proton donor
Binding site1973-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site218-2193-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionpyridoxine 5'-phosphate synthase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine 5'-phosphate synthase
  • EC number
  • Short names
    PNP synthase

Gene names

    • Name
      pdxJ
    • ORF names
      D6D77_07560

Organism names

Accessions

  • Primary accession
    A0A198WZQ7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer; tetramer of dimers.

Family & Domains

Sequence similarities

Belongs to the PNP synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    27,232
  • Last updated
    2016-10-05 v1
  • Checksum
    1CF61C34ED7F37C7
MNIPLLGVNIDHIATLRNARGVGYPCPIKGALICEQAGASGITLHLREDRRHIQDEDVYELIGQLTTRMNLEMAVTDEMLNIALKVRPAWVCLVPEKRQELTTEGGLDVVNLSNIQAFIHSLQQADIKVSLFIDPDLHQIDAAIALGADAIELHTGAYAQATLQNNQKLVDKELDRIQKAVAMAQKKSSLLINAGHGLTRDNVAAIAQIDGIHELNIGHALISDAIFMGLDNAVKAMKMAFIQDKMTNH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QZGP01000005
EMBL· GenBank· DDBJ
RKL88481.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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