A0A194PGG9 · A0A194PGG9_PAPXU
- ProteinSortilin-related receptor
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2211 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | multivesicular body membrane | |
Cellular Component | plasma membrane | |
Cellular Component | recycling endosome membrane | |
Cellular Component | transport vesicle membrane | |
Biological Process | endocytosis | |
Biological Process | post-Golgi vesicle-mediated transport | |
Biological Process | vacuolar transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSortilin-related receptor
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Lepidoptera > Glossata > Ditrysia > Papilionoidea > Papilionidae > Papilioninae > Papilio
Accessions
- Primary accessionA0A194PGG9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein
Early endosome membrane ; Single-pass type I membrane protein
Endoplasmic reticulum membrane ; Single-pass type I membrane protein
Endosome membrane ; Single-pass type I membrane protein
Endosome, multivesicular body membrane ; Single-pass type I membrane protein
Golgi apparatus membrane ; Single-pass type I membrane protein
Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein
Recycling endosome membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 2137-2161 | Helical | ||||
Sequence: AVWWGCGAAVVGVAALGAALLYSVV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-24 | |||||
Sequence: MFTVIRRRISFVALLYFIPCVVSS | ||||||
Chain | PRO_5008263225 | 25-2211 | Sortilin-related receptor | |||
Sequence: HEYETWEKSLYVAQEPFEGSGKLFIINKFDTVGDGSHFERKKREAPTTPAPALEKNISTWTTHLNDSHQQLMVHWVGEGSKVIICLARDSSPRSNGTLSPSALFISYNYGQTIVNKTESFRLDDTPNSGYAQLDRFYNHPKHPEFCVFVDSINKRLYYTDDNGQNIHRSELTFHPSELLFDEDNPKRFVVLDKVGRNRMLYMTFNGGKTFTLIQSYVKTFYWSSGPGFPKMFYLERWEPNRSSTVLSVSDPEDMINAKVLFADAKEFQIKGDYMFAMRQKDNNTFDLYISHQRGPFYKAEFQTELDRRKFHIADVTDKRIFISVMHTENLTNLYVSEISNNFTQYNFVLSLEQVLCYFPQGNWKDSWLEDVTDDAFTDLYRVEGLKGIYIASKVNSKSLIADIEPEHLVSLITFDHGVTWSPIKPPAEDENGKPLSCIDSNDSEKSCSLHLCQKFSQLYPVTSPPGNVISNAMRLLCIAALAAVKRVGGLRVKHVTWNLQVVGSNPAISASIMSSKSAPGIIMATGVVGRSLKGIPGVYLSRVAGLTWKRILKDFYFFNYGDHGGVLVAVKYFKMLSETREILYSTNEGIEWNSYQFNANDLRIYGLMTEPGENTTVFTMFGSANEQHQWIIITIDLQKAFPRNCTADDYKDWSPSPPDTTATCVLGTRDVFQRRLAHTNCYNGIDYDGPIRKEVCECGRRDFECDFGFVLSRNVCVHNKSSKYDPYSIPPSCRPGDYYERTKGYRKIDGDVCTTSGYLPYNPDVIPCPLDEPTEFLLVALRDKIARIDLSDNTTIFPIKDQQNIVAIEFDMKNNCIYWADIEVDKISRQCFETGFVQEVVVDTDLASIEGMALDWISNVLFFVDGMRKKIEAVRTDLSSEGRMRVTILGPDVLSKPRGIVVHPKAGYLFWTDWDRNNPSVSRSNLDGSHIVRLFEKPIVQWPNGITIDQMSERIYWVDAMEDYIASADLNGQYFKKILVNDEKVSHPFAVAVLKDKMYWDDWKAKSIFIADKDNGQNVITINGSFSGLMGLKVFAHFIQHGSNACSYKNTSCDALCLGGPGNSFSCLCPDGFVKSHGKCLCPNLVEPYANLTCPKKPGATCASDQFSCKNDMCIAQSWRCDGNDDCGDGSDEAGCVCAPPRVACDNGSCYLPQWRCDGDIDCSDMTDEKDCGKHNCSENEFQCGNGNCVDKRWVCDGDNDCKDDSDERNCTSQVKRPNTQVNCSVHSFACNDSSGMCIPNSWVCDNETDCPGGEDERDERCRNSTCAPYMFRCPSGKCIYKSWVCDGENDCSDVESSDEKNCTHIGHSKLLPRPTTESPFSFPANSSCLDWMIQCDNGNCLPYWWRCDGINDCGDNSDEVACGVHFVEPKTINRADSVRQKCGKTRFTCSPGVCIPLSWVCDSQEDCVDGSDEHSCRAWATATPLPLPSCGALETTCRDGGCVLTAKICDGVPDCVDHSDETHCTMKASKPSGACPGDQFECDEGTRCVWRGALCDGRQDCYDGSDETNCSSHEHNYHYVSLGVDQSSINSTSFLVSCWLAQQQRVLYSFLPSIAKVSDGIWRNMTWTTDSVYRFTGLEPYTNYNVTFYIRDSKSNKTYPSMKYVNTTTGEGVPSPPLRVSVRQMIGSRVNVIWDPPASPRGRLRRYTLYYAPPLPPAQKVVFVTHHEPVSLTVRGYFKPNTNYSFWVTATNNAYTSNSSEVMYLTFDEVGDVDDLKNISVTRLANNSVSVKWDKIRSVDGYIVSTQLPLLYSRLQPIRTKENNVTLKNLPPGVKIFIHVMAYKGSMIGEPVTEVIITEGERDEMLNMTAILLKEKRTAVLLSWSPPLADRYNGKELKYQVIYTDAAHWRIPTDLKEDHEKKIITTNTSVVIDGLHACETYVFTVSLLGGPVTKYKEIVTRENPKAPIKDLDYEYNKEKSELKIKWHINCNALSEAVPYRLEITELTHNKVSRYALNATRNSSLEHIIENVPVGGRFNICVAAHVEGASKRCIDVRTGALPAPRGLVAWLAPNGHLVLNWQHVEGPDTPKHKYQVIVSEKEIPDDLVQPSADMRVEEAERSPLLLAVTAPAAARPLYVSVRAVTHDGYYSELSEVNTLTMEDSVEEMGTASAVWWGCGAAVVGVAALGAALLYSVVRQRRLARSFLRLSAHTPRYDSRRGQATIEHDDDDVPPIQGFSDDEPLVIA | ||||||
Disulfide bond | 1126↔1138 | |||||
Sequence: CASDQFSCKNDMC | ||||||
Disulfide bond | 1133↔1151 | |||||
Sequence: CKNDMCIAQSWRCDGNDDC | ||||||
Disulfide bond | 1145↔1160 | |||||
Sequence: CDGNDDCGDGSDEAGC | ||||||
Disulfide bond | 1162↔1174 | |||||
Sequence: CAPPRVACDNGSC | ||||||
Disulfide bond | 1169↔1187 | |||||
Sequence: CDNGSCYLPQWRCDGDIDC | ||||||
Disulfide bond | 1181↔1196 | |||||
Sequence: CDGDIDCSDMTDEKDC | ||||||
Disulfide bond | 1201↔1213 | |||||
Sequence: CSENEFQCGNGNC | ||||||
Disulfide bond | 1208↔1226 | |||||
Sequence: CGNGNCVDKRWVCDGDNDC | ||||||
Disulfide bond | 1220↔1235 | |||||
Sequence: CDGDNDCKDDSDERNC | ||||||
Disulfide bond | 1291↔1303 | |||||
Sequence: CAPYMFRCPSGKC | ||||||
Disulfide bond | 1298↔1316 | |||||
Sequence: CPSGKCIYKSWVCDGENDC | ||||||
Disulfide bond | 1353↔1365 | |||||
Sequence: CLDWMIQCDNGNC | ||||||
Disulfide bond | 1360↔1378 | |||||
Sequence: CDNGNCLPYWWRCDGINDC | ||||||
Disulfide bond | 1372↔1387 | |||||
Sequence: CDGINDCGDNSDEVAC | ||||||
Disulfide bond | 1407↔1419 | |||||
Sequence: CGKTRFTCSPGVC | ||||||
Disulfide bond | 1414↔1432 | |||||
Sequence: CSPGVCIPLSWVCDSQEDC | ||||||
Disulfide bond | 1426↔1441 | |||||
Sequence: CDSQEDCVDGSDEHSC | ||||||
Disulfide bond | 1455↔1467 | |||||
Sequence: CGALETTCRDGGC | ||||||
Disulfide bond | 1462↔1480 | |||||
Sequence: CRDGGCVLTAKICDGVPDC | ||||||
Disulfide bond | 1474↔1489 | |||||
Sequence: CDGVPDCVDHSDETHC | ||||||
Disulfide bond | 1520↔1535 | |||||
Sequence: CDGRQDCYDGSDETNC |
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for repeat, domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 931-976 | LDL-receptor class B | ||||
Sequence: GYLFWTDWDRNNPSVSRSNLDGSHIVRLFEKPIVQWPNGITIDQMS | ||||||
Repeat | 977-1021 | LDL-receptor class B | ||||
Sequence: ERIYWVDAMEDYIASADLNGQYFKKILVNDEKVSHPFAVAVLKDK | ||||||
Domain | 1638-1735 | Fibronectin type-III | ||||
Sequence: VPSPPLRVSVRQMIGSRVNVIWDPPASPRGRLRRYTLYYAPPLPPAQKVVFVTHHEPVSLTVRGYFKPNTNYSFWVTATNNAYTSNSSEVMYLTFDEV | ||||||
Domain | 1740-1827 | Fibronectin type-III | ||||
Sequence: DLKNISVTRLANNSVSVKWDKIRSVDGYIVSTQLPLLYSRLQPIRTKENNVTLKNLPPGVKIFIHVMAYKGSMIGEPVTEVIITEGER | ||||||
Domain | 1829-1928 | Fibronectin type-III | ||||
Sequence: EMLNMTAILLKEKRTAVLLSWSPPLADRYNGKELKYQVIYTDAAHWRIPTDLKEDHEKKIITTNTSVVIDGLHACETYVFTVSLLGGPVTKYKEIVTREN | ||||||
Domain | 2027-2128 | Fibronectin type-III | ||||
Sequence: APRGLVAWLAPNGHLVLNWQHVEGPDTPKHKYQVIVSEKEIPDDLVQPSADMRVEEAERSPLLLAVTAPAAARPLYVSVRAVTHDGYYSELSEVNTLTMEDS | ||||||
Compositional bias | 2182-2198 | Basic and acidic residues | ||||
Sequence: SRRGQATIEHDDDDVPP | ||||||
Region | 2182-2211 | Disordered | ||||
Sequence: SRRGQATIEHDDDDVPPIQGFSDDEPLVIA |
Sequence similarities
Belongs to the VPS10-related sortilin family. SORL1 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,211
- Mass (Da)248,390
- Last updated2016-10-05 v1
- Checksum3620AF0AA8C2A8F1
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 2182-2198 | Basic and acidic residues | ||||
Sequence: SRRGQATIEHDDDDVPP |
Keywords
- Technical term