A0A193H8B6 · A0A193H8B6_9TOMB

Function

function

RNA-dependent RNA polymerase that plays an essential role in the virus replication.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionnucleotide binding
Molecular FunctionRNA binding
Molecular FunctionRNA-dependent RNA polymerase activity
Biological Processviral RNA genome replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA-directed RNA polymerase
  • EC number

Organism names

  • Taxonomic identifier
  • Strain
    • T46
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Kitrinoviricota > Tolucaviricetes > Tolivirales > Tombusviridae > Procedovirinae > Tombusvirus > Tombusvirus pelargonii

Accessions

  • Primary accession
    A0A193H8B6

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane166-188Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain558-675RdRp catalytic

Sequence similarities

Belongs to the tombusviridae RNA polymerase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    852
  • Mass (Da)
    95,613
  • Last updated
    2016-10-05 v1
  • Checksum
    8513AE08BE0CEF1B
MEGLKAESTTTVGINCNFQQTVMTETGDKVMFGSLPSVLDRPVAKRNYYRTLSNWVLTYTKTGKIEDTHDNAWSYVEDLVKTDFNAKYDWLAKRGVAREYRTAVGLAIIPGIPAIVANTRIVTGTCEVARVAVKLPKVLNILSRFTHVSVKVPYFYPRVDVSARGVLIGLAAAAALVPICAGIAYATLPREKLSVFRLKTEVRVHMEDEKEATDLLLVEPARELKGKDGEDLLTGSRLTKVIASTRRPRRRPYAAKIAQVARAKVGYLKNSPENRLIYQRVLIEIMDKDCVRYVDRDVILPLAIGCCFVYPDGVEESAALWGSQESLGVKXGGLVRLPGVVTQINRDIPSDVLLPQEVLEVRAGPPNAKDRNIFMVAGCPSQARFLVHNHCLKNLKRGLVERVFCVERNGKLTRTPQPTKGAFGRLSPFRKAVCEKVGVAHRLGYDGFLSYYNGAKLRTYTRAVESLHITPVSERDSHLTTFVKAEKISTSKGDPAPRVIQPRNPRYNVELGRYLRHMESKLMKAVDGVFGETTCIKGYTADEVGAIFRAKWDRFDKPVAIGLDASRFDQHCSVEALQYEHSFYRAMYPGNKLLSKLLEWQLHNKGKGYVPDGTITYRKEGCRMSGDINTSLGNYLLMCAMVHGYMRHLGINEFSLANCGDDCVLILERRNLKQVQRTLPEYFLNLGYTMKVELPVFQLEEVEFCQAHPVQFQGGWKMVRNVRTAMSKDVHCVNNIRDLATRRAWSNAQHHGGLALSAGIPVVEAFYSRFKLYDTPRKHQRIDTVTNVHKWRGSGGSYVVTPESRASFWAAFGLTGDEQLALEDRLERWEMDLFGEEGVDAHEPSILDSAVA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KU187189
EMBL· GenBank· DDBJ
ANN90559.1
EMBL· GenBank· DDBJ
Genomic RNA

Genome annotation databases

Similar Proteins

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