A0A191HU08 · A0A191HU08_9FIRM

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site37Na+ (UniProtKB | ChEBI); structural
Binding site40Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • ORF names
      AZF37_03585

Organism names

Accessions

  • Primary accession
    A0A191HU08

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-50Helical
Transmembrane62-87Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    90
  • Mass (Da)
    9,818
  • Last updated
    2016-10-05 v1
  • Checksum
    AF1D398EB8439DED
MLANVIGCFLIGFLMSYFLSSGKNNPFMPFLITGFLGGFTTFSTFSYETISLFTNGAIAKGLINLSLTLFFCFLGVALGIFLGKLIFSRN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP014606
EMBL· GenBank· DDBJ
AMP20370.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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