A0A183LAI3 · A0A183LAI3_9TREM

  • Protein
    Katanin p60 ATPase-containing subunit A-like 2
  • Gene
    KATNAL2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.

Catalytic activity

  • n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.
    EC:5.6.1.1 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

153350100150200250300350400450500
TypeIDPosition(s)Description
Binding site261-268ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmicrotubule
Cellular Componentspindle pole
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionisomerase activity
Molecular Functionmicrotubule binding
Molecular Functionmicrotubule severing ATPase activity
Biological Processmicrotubule severing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Katanin p60 ATPase-containing subunit A-like 2
  • EC number
  • Short names
    Katanin p60 subunit A-like 2
  • Alternative names
    • p60 katanin-like 2

Gene names

    • Name
      KATNAL2
    • ORF names
      SMRZ_LOCUS808

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Zambia
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Platyhelminthes > Trematoda > Digenea > Strigeidida > Schistosomatoidea > Schistosomatidae > Schistosoma

Accessions

  • Primary accession
    A0A183LAI3

Proteomes

Subcellular Location

Cytoplasm, cytoskeleton
Cytoplasm
Note: Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    533
  • Mass (Da)
    59,788
  • Last updated
    2016-09-07 v1
  • Checksum
    253D5974F7C66F76
MKTKEEQRSTARKKNLLILVMHYLSEEGNILELPKNYQVSYIFYIIDVILDKLLQCEKKRHGGSSIKTKNSIHDFEQNHSSNILNPEENSGVTKNRACNGLAVQGRQDPLVQISGRIVKSGISPNVPNGSSITSLNHLDPTQNSFLSPSTRQNFPRQITDYRAIINQETRLPLEENQLSEDPQERLLKPLGSYLGYTGEWRSLALTISRDIFLQNPNVRWDDIIGLSSAKRLVKEAVVYPIKYPQLFAGILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARFHAPSTIFLDELDSLMSQRGSLSGYSSSGGGNSNISVGNEHEGSRRMKTELLMQMDGLAKSDDLVFLLAASNLPWELDHAMLRRLEKRILVDLPNKEARIHMFESFLPPVIGQGTSGGLQLKCYLDYDVAAELTEGYSGSDIRLVCKEAAMRVVRKIFDILENSSIESKKFCTILFFFYLPQTQIHFDPITTDDVKAAISSTMPSARQLAGKYLEWQQQFGSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UZAI01000158
EMBL· GenBank· DDBJ
VDO49337.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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