A0A182R076 · A0A182R076_9DIPT

  • Protein
    Acylglycerol kinase, mitochondrial
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Catalytic activity

  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-sn-glycerol + ATP = 1-hexadecanoyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + ATP = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • N-(hexanoyl)sphing-4-enine + ATP = N-hexanoylsphing-4-enine 1-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.107 (UniProtKB | ENZYME | Rhea)
  • a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a monoacylglycerol + ATP = a monoacyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.94 (UniProtKB | ENZYME | Rhea)
  • an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.138 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Lipid metabolism; glycerolipid metabolism.

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrial intermembrane space
Molecular Functionacylglycerol kinase activity
Molecular FunctionATP-dependent diacylglycerol kinase activity
Molecular Functionceramide kinase activity
Molecular FunctionD-erythro-sphingosine kinase activity
Biological Processceramide biosynthetic process
Biological Processglycerolipid metabolic process
Biological Processphosphorylation
Biological Processsphingosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acylglycerol kinase, mitochondrial
  • EC number
  • Alternative names
    • Multiple substrate lipid kinase

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • FAR1
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Nematocera > Culicoidea > Culicidae > Anophelinae > Anopheles

Accessions

  • Primary accession
    A0A182R076

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain61-206DAGKc

Sequence similarities

Belongs to the AGK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    446
  • Mass (Da)
    49,976
  • Last updated
    2016-09-07 v1
  • MD5 Checksum
    A847449E41C4D718832C84659C36E3D9
MAFVIRFAKAVRNNWKKSTVFASALAYGVSYSNEKYEIKQLMRYYCTEASRYGDVKIGLNQRPPKVLVLLNPAANRKSSEEDFQSYCEPILHLAGFEVDVVKTDSEGHARRYVEELATLPDALIVGGGDGTLSEAVSGMKRRQDGAQCPIGVLPLGRTNTLAMKLFSAEGAKNTDLENVRSMANAAYAVIAGKKEKTDVMRIEVLPSAADETPPEKPVYAVGALQWGAFRDILSLRDKYWYTASLRDYTAFLFNAFDSAHTWNCKAKIAYTEPCTGCSNCYRDFDDQWAAAKKQEQQPRRWWSVFVPRSKTAPKTDYSKIVNEKCSVRHEIEVDPAEVVIKTGNVTSTEEGESVGETSTKLDVVVGEQVDSSFSFIGGSWGRVKNRKFLECPSKEHISVRTVELHPARLKVEESDPELYYSIDNEAYEVRPVRITLVPKAVEIFTF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AXCN02000446
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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