A0A182Q0Z2 · A0A182Q0Z2_9DIPT
- ProteinPhosphodiesterase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids845 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Cofactor
Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 558 | Proton donor | |||
Binding site | 558-562 | AMP (UniProtKB | ChEBI) | |||
Binding site | 562 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 600 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 601 | AMP (UniProtKB | ChEBI) | |||
Binding site | 601 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 601 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 710 | AMP (UniProtKB | ChEBI) | |||
Binding site | 710 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 761 | AMP (UniProtKB | ChEBI) | |||
GO annotations
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphodiesterase
- EC number
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Nematocera > Culicoidea > Culicidae > Anophelinae > Anopheles
Accessions
- Primary accessionA0A182Q0Z2
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-48 | Disordered | |||
Compositional bias | 24-45 | Polar residues | |||
Domain | 476-804 | PDEase | |||
Region | 798-818 | Disordered | |||
Compositional bias | 802-816 | Polar residues | |||
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length845
- Mass (Da)94,274
- Last updated2016-09-07 v1
- MD5 ChecksumEB3D025C801EE1DA84C7566E65140B48
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 24-45 | Polar residues | |||
Compositional bias | 802-816 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AXCN02000801 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AXCN02000802 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AXCN02000803 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |