A0A182D3W6 · A0A182D3W6_BLAVI
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids772 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H2O + H+(in) = 2 phosphate + 2 H+(out)
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 523 | Determinant of potassium independence | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Blastochloridaceae > Blastochloris
Accessions
- Primary accessionA0A182D3W6
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 54-74 | Helical | ||||
Sequence: WMTALVLIIIGGLLSIAYGIW | ||||||
Transmembrane | 108-126 | Helical | ||||
Sequence: YITIAIVGVVIFALVAWLL | ||||||
Transmembrane | 132-153 | Helical | ||||
Sequence: FGFAIGAVLSGAAGFIGMNVSV | ||||||
Transmembrane | 173-200 | Helical | ||||
Sequence: LAFKAGAVTGLLVAGLALLGVAVYFTVL | ||||||
Transmembrane | 212-231 | Helical | ||||
Sequence: VVVDALVALGFGASLISIFA | ||||||
Transmembrane | 289-307 | Helical | ||||
Sequence: YAVTAVATMVLAAIFFAGQ | ||||||
Transmembrane | 313-335 | Helical | ||||
Sequence: IIIYPLAIGAVCVATSIAGTFFV | ||||||
Transmembrane | 347-370 | Helical | ||||
Sequence: LYKGLIATGVLSIAAIALVNLVLF | ||||||
Transmembrane | 390-412 | Helical | ||||
Sequence: LFACAVLGFVVTALIVVITEYYT | ||||||
Transmembrane | 433-457 | Helical | ||||
Sequence: NIIQGLAVSLESTALPTLVIIAGIL | ||||||
Transmembrane | 463-485 | Helical | ||||
Sequence: AGLFGIAVAVTAMLSLAGIIVAL | ||||||
Transmembrane | 528-545 | Helical | ||||
Sequence: GYAIGSAGLGALVLFAAY | ||||||
Transmembrane | 565-590 | Helical | ||||
Sequence: VVIDFSLSNPYVVVGLLFGGLLPYLF | ||||||
Transmembrane | 644-664 | Helical | ||||
Sequence: IIPSLLPVLSPVVVYFVIYFV | ||||||
Transmembrane | 676-695 | Helical | ||||
Sequence: FSSVGALLLGVIVTGVFVAI |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 720-740 | Disordered | ||||
Sequence: GKVHQKGSEAHKASVTGDTVG |
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length772
- Mass (Da)78,593
- Last updated2016-09-07 v1
- ChecksumA3D1FAE57C3594AC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP014854 EMBL· GenBank· DDBJ | BAS00140.1 EMBL· GenBank· DDBJ | Genomic DNA |