A0A182D3W6 · A0A182D3W6_BLAVI

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

TypeIDPosition(s)Description
Site523Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      BV133_2546

Organism names

Accessions

  • Primary accession
    A0A182D3W6

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane54-74Helical
Transmembrane108-126Helical
Transmembrane132-153Helical
Transmembrane173-200Helical
Transmembrane212-231Helical
Transmembrane289-307Helical
Transmembrane313-335Helical
Transmembrane347-370Helical
Transmembrane390-412Helical
Transmembrane433-457Helical
Transmembrane463-485Helical
Transmembrane528-545Helical
Transmembrane565-590Helical
Transmembrane644-664Helical
Transmembrane676-695Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region720-740Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    772
  • Mass (Da)
    78,593
  • Last updated
    2016-09-07 v1
  • Checksum
    A3D1FAE57C3594AC
MGDDSAAIARSGLFARKPTLLGGSRENGPAGANVVPAVSVAACGPATDETKVGWMTALVLIIIGGLLSIAYGIWATKSLMAADSGSQRMQEIAAAIREGATAYLKRQYITIAIVGVVIFALVAWLLSPTVAFGFAIGAVLSGAAGFIGMNVSVRANVRTAQAATKSLAGGLELAFKAGAVTGLLVAGLALLGVAVYFTVLTQFMGLAANDRVVVDALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTAVATMVLAAIFFAGQPILDTIIIYPLAIGAVCVATSIAGTFFVKLGPSQSIMGALYKGLIATGVLSIAAIALVNLVLFGGFGTEFKTNGGVAFTSGDLFACAVLGFVVTALIVVITEYYTGTGKRPVVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILSTYSLAGLFGIAVAVTAMLSLAGIIVALDAFGPVTDNAGGIAEMSGLPKEVRKATDALDAVGNTTKAVTKGYAIGSAGLGALVLFAAYSEDLKFFSANPTEFPYFKDVVIDFSLSNPYVVVGLLFGGLLPYLFGAMGMMAVGRAASAIVEEVRRQFRENPGIMDYKVKPDYGRAVDMLTKAAIKEMIIPSLLPVLSPVVVYFVIYFVAGGGAAGKSAAFSSVGALLLGVIVTGVFVAISMTSGGGAWDNAKKSFEDGFTDKDGKVHQKGSEAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAILAHH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP014854
EMBL· GenBank· DDBJ
BAS00140.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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