A0A178WK00 · A0A178WK00_ARATH
- ProteinCDP-diacylglycerol--serine O-phosphatidyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids425 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
Catalytic activity
- a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H+
Pathway
Lipid metabolism.
Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | CDP-diacylglycerol-serine O-phosphatidyltransferase activity | |
Molecular Function | L-serine-phosphatidylethanolamine phosphatidyltransferase activity | |
Biological Process | phosphatidylethanolamine biosynthetic process | |
Biological Process | phosphatidylserine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCDP-diacylglycerol--serine O-phosphatidyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA0A178WK00
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 77-99 | Helical | ||||
Sequence: GVWAMIAVFLAYSLLQAPSTVLI | ||||||
Transmembrane | 105-125 | Helical | ||||
Sequence: IWRLVHGMAVIYLVALTFLLF | ||||||
Transmembrane | 228-247 | Helical | ||||
Sequence: IVLDILICNWFGIWAGMYTV | ||||||
Transmembrane | 299-322 | Helical | ||||
Sequence: VLTLCIIFLTVELNTFFLKFSLWI | ||||||
Transmembrane | 360-386 | Helical | ||||
Sequence: VGAFCWLSLGICIVELLICIKFGSGLY | ||||||
Transmembrane | 392-414 | Helical | ||||
Sequence: LWVVTLWGSVGLGLVAFLLSWTW |
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-18 | Basic and acidic residues | ||||
Sequence: MEPNGYRKERRKEQHLGR | ||||||
Region | 1-23 | Disordered | ||||
Sequence: MEPNGYRKERRKEQHLGRMNGGG |
Sequence similarities
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length425
- Mass (Da)49,518
- Last updated2016-09-07 v1
- ChecksumD115455EE19654FD
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-18 | Basic and acidic residues | ||||
Sequence: MEPNGYRKERRKEQHLGR |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LUHQ01000001 EMBL· GenBank· DDBJ | OAP18639.1 EMBL· GenBank· DDBJ | Genomic DNA |