A0A178W755 · A0A178W755_ARATH

Function

function

Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) at position 37 in tRNAs that read codons beginning with adenine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular FunctionN6-threonylcarbomyladenosine methylthiotransferase activity
Molecular FunctiontRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Threonylcarbamoyladenosine tRNA methylthiotransferase
  • EC number
  • Alternative names
    • tRNA-t(6)A37 methylthiotransferase

Gene names

    • Ordered locus names
      At1g72090
      , AXX17_At1g66210

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Landsberg erecta
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0A178W755

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane580-600Helical

Keywords

  • Cellular component

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias30-53Polar residues
Region30-55Disordered
Domain64-172MTTase N-terminal
Domain193-425Radical SAM core
Domain423-488TRAM

Sequence similarities

Belongs to the methylthiotransferase family. CDKAL1 subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    601
  • Mass (Da)
    65,496
  • Last updated
    2017-04-12 v1
  • Checksum
    AAC13F7EFCE3DA3D
MEDIEDLLAGGVGGAPPGFRLPLNAVGINPKTNKSKRISSKPDQITASNRDSLAPPSMKIPGTQTIYIKTFGCSHNQSDSEYMAGQLSAFGYALTEVPEEADLWLINTCTVKSPSQSAMSTLITRGRSGKKPLVIAGCVPQGSRDLKELEGVSVVGVQQIDRVVEIVEETLKGHEVRLLTRKTLPALDLPKVRRNNFIEILPINVGCLGACTYCKTKHARGHLGSYTVDSLVERVRTVISEGVKEIWLSSEDTGAYGRDIGVNLPILLNAIVKELPSDQSTMLRIGMTNPPFILEHLKEIAAVLRHPCVYTFLHVPVQSGSDSVLTAMNREYTASEFRTVVDTLTELVPGMQIATDIICGFPGETDEDFSQTVELIKDYKFPQVHISQFYPRPGTPAAKMKKVQSKIVKQRSRELTSVFEAFAPYTGMECREERIWITEVATDGIHLVGHTKGYVQVLVTGPESMLGTSAMARITSVGRWSVFGEVIETFSSANRETKSREETKLPCSSNVSTCETCTCSAESCGEERSGEACNISGNISGQDDNKGKSKKEEKEVQEVVVPGSSVANWGFIDKALVCGVFVSSVTILVLLISIACRVLLR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias30-53Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LUHQ01000001
EMBL· GenBank· DDBJ
OAP13551.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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