A0A178VHJ5 · A0A178VHJ5_ARATH

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site220
Binding site309Mg2+ 1 (UniProtKB | ChEBI)
Binding site309Mg2+ 2 (UniProtKB | ChEBI)
Binding site313Mg2+ 1 (UniProtKB | ChEBI)
Binding site371substrate
Binding site486Mg2+ 2 (UniProtKB | ChEBI)
Binding site490Mg2+ 2 (UniProtKB | ChEBI)
Binding site512substrate

GO annotations

AspectTerm
Molecular Functionketol-acid reductoisomerase activity
Molecular Functionmetal ion binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ketol-acid reductoisomerase
  • EC number
  • Alternative names
    • Acetohydroxy-acid reductoisomerase
    • Alpha-keto-beta-hydroxylacyl reductoisomerase

Gene names

    • ORF names
      AN1_LOCUS16241
      , AT9943_LOCUS13980
      , C24_LOCUS16122
    • Ordered locus names
      AXX17_At3g53150

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Landsberg erecta
    • cv. An-1
    • cv. C24
    • cv. Cdm-0
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0A178VHJ5
  • Secondary accessions
    • A0A5S9XM31

Proteomes

Genome annotation databases

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-20Disordered
Domain102-300KARI N-terminal Rossmann
Domain301-449KARI C-terminal knotted
Domain450-586KARI C-terminal knotted

Sequence similarities

Belongs to the ketol-acid reductoisomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    591
  • Mass (Da)
    63,812
  • Last updated
    2016-09-07 v1
  • Checksum
    003C41A69B2C0F4F
MAAATSSIAPSLSCPSPSSSSKTLWSSKARTLALPNIGFLSSSSKSLRSLTATVAGNGATGSSLAARMVSSSAVKAPVSLDFETSVFKKEKVSLAGYEEYIVRGGRDLFKHLPDAFKGIKQIGVIGWGSQGPAQAQNLRDSLVEAKSDIVVKIGLRKGSRSFEEARAAGFTEESGTLGDIWETIAGSDLVLLLISDAAQADNYEKIFSHMKPNSILGLSHGFLLGHLQSSGLDFPKNISVVAVCPKGMGPSVRRLYVQGKEINGAGINASFAVHQDVDGRAADVALGWSVALGSPFTFATTLEQEYRSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAYKNTVECITGTISRTISTQGMLAVYNSLSEEGKKDFETAYSASFYPCMEILYECYEDVQSGSEIRSVVLAGRRFYEKEGLPAFPMGNIDQTRMWKVGERVRKSRPAGDLGPLYPFTAGVYVALMMAQIEILRKKGHSYSEIINESVIESVDSLNPFMHARGVSFMVDNCSTTARLGSRKWAPRFDYILTQQALVAVDSGAAINRDLISNFFSDPVHGAIEVCAQLRPTVDISVPADADFVRPELRQSSN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CACSHJ010000089
EMBL· GenBank· DDBJ
CAA0387255.1
EMBL· GenBank· DDBJ
Genomic DNA
LR881468
EMBL· GenBank· DDBJ
CAD5326197.1
EMBL· GenBank· DDBJ
Genomic DNA
LUHQ01000003
EMBL· GenBank· DDBJ
OAP05158.1
EMBL· GenBank· DDBJ
Genomic DNA
CACRSJ010000106
EMBL· GenBank· DDBJ
VYS60806.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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