A0A178UXW6 · A0A178UXW6_ARATH
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids572 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 99 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 368 | Nucleophile | ||||
Sequence: T | ||||||
Binding site | 386-388 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: TIN | ||||||
Binding site | 410 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 440-441 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: SS | ||||||
Binding site | 462 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: G |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | acyltransferase activity | |
Molecular Function | glutathione hydrolase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA0A178UXW6
Proteomes
Genome annotation databases
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MSLVRTVTIVLFIIAFLQNAAA | ||||||
Chain | PRO_5038213792 | 23-572 | Glutathione hydrolase | |||
Sequence: QKRQQSIVKSRGAVATDDGRCSVIGMRVLREGGNAIDASVAAALCLGVVSPASSGIGGGAFTVVKIAGGKEIAYDSRETAPLRATENMYGGNVDLKKKGALSVGVPGEVAGLFTAWKQHGKLPWKRLVTPAEKLAEGFKISKYLYMQMNATRSDILADKGLSDLFVSNGELKKPGTICHNPKLALTLKLIGEYGPKAFYNGTVGVNLARDIKKSGGIITLKDLQSYRVKIKEPLSADILGYRVLGMPPPSSGGAAMMLVLNILSQYGIPSGVSGPLGVHRLIEALKHAFAVRMNLGDPDFTDVTKVVSDMLSPKFAKDLKSKINDQKTFDPKYYGGMWNQIDDHGTSHLSIIDRERNAVSMTSTINGYFGALMLSPSTGIVLNNEMDDFSIPMKSNGNLDVPPPAPANFIRPGKRPLSSMSPTIVLKDGKVKAAVGASGGANIIAGTTEVYLNHFFLKMDPLSSVLAPRIYHQLIPNRASYENWTTVFNDHFEIPKATRVVLEKKGHVLSPIAGGTIAQFIVQESGENSGGRSELVAVSDPRKGGFPSGY |
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length572
- Mass (Da)61,190
- Last updated2016-09-07 v1
- Checksum67E3848EDCC2795F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LUHQ01000004 EMBL· GenBank· DDBJ | OAO97511.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CACRSJ010000109 EMBL· GenBank· DDBJ | VYS65419.1 EMBL· GenBank· DDBJ | Genomic DNA |