A0A178HDU8 · A0A178HDU8_9LACT

  • Protein
    Polyphosphate kinase
  • Gene
    ppk
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

1731100200300400500600700
Type
IDPosition(s)Description
Binding site62ATP (UniProtKB | ChEBI)
Binding site393Mg2+ (UniProtKB | ChEBI)
Binding site423Mg2+ (UniProtKB | ChEBI)
Active site453Phosphohistidine intermediate
Binding site486ATP (UniProtKB | ChEBI)
Binding site582ATP (UniProtKB | ChEBI)
Binding site610ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentpolyphosphate kinase complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpolyphosphate kinase activity
Biological Processphosphorylation
Biological Processpolyphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyphosphate kinase
  • EC number
  • Alternative names
    • ATP-polyphosphate phosphotransferase
    • Polyphosphoric acid kinase

Gene names

    • Name
      ppk
    • ORF names
      DBT54_05570

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • UMB7480
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Aerococcaceae > Aerococcus

Accessions

  • Primary accession
    A0A178HDU8

Proteomes

Subcellular Location

PTM/Processing

Post-translational modification

An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-128Polyphosphate kinase N-terminal
Domain139-321Polyphosphate kinase middle
Domain350-514Polyphosphate kinase C-terminal
Domain521-691Polyphosphate kinase C-terminal

Sequence similarities

Belongs to the polyphosphate kinase 1 (PPK1) family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    731
  • Mass (Da)
    84,541
  • Last updated
    2016-09-07 v1
  • MD5 Checksum
    F61D46B93BCC58724D38B48E67359E2C
MSTTSNNQKNTQSLQAENSAAHYYYNRELSWLDFNYRCVEEASDPNNPLLEQLNFLGIVSSNLDEFIMVRFAGVYNQYLDGVQVAENKTQMSPKQLMQGIHDRNTRNVKAQYTRYHDMVELLDEKGYHLKSVADLSEAQKAQVKEQFEELILPTLTAIGIDAYRPFPHLKNHALNILVELEKDQNSYIAVVPIPTLLKRYLTLDEGEGKAYVLVEDVVIHGLNALFKGYTIKRRIPFRIARNADFELNEDDVMDLLDVMEDHVKNRLHGKTVRIEWDTRWETPNDHNNEDFLATVQPYLKVPEEGLYPINGPLDLTFLFDLVDDISEDHPEWMYPDFEPVEYPNYHGENLYQLIKKGDLFFHHPYDSFKPILSFVDHAASDPKTVAIKMTLYRVSKHSPIVKSLKKAAENGKEVTVLVELKARFDEENNVHWARELEDAGCHVLYGLSELKTHSKITLVVRREAGKIQRYIHLGTGNYNDKTAKQYTDMGILSTNEALTSDGSKFFNFLSGYSEVPDYEALHVSPFAIRDSLTDYIDEEIENQKKYGNGRIIAKMNSLTDKPLIKKLYEASQAGVQIDLIIRGICCLRPQVEGLSENIRVRSIVGRFLEHSRIYYFYRNGQKHVFLSSADMMTRNMIRRVEIEFPIIDQDIEAQIIHFLEVELADNQKARELGSDGVYRHVKSGDKPINSQEQMMQEAESRRNESVMRITPSSPNFFKRMTRFLTNRHKDD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QMHM01000008
EMBL· GenBank· DDBJ
RAV79455.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help