A0A178HDU8 · A0A178HDU8_9LACT
- ProteinPolyphosphate kinase
- Geneppk
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids731 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Catalytic activity
- [phosphate](n) + ATP = [phosphate](n+1) + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 62 | ATP (UniProtKB | ChEBI) | |||
Binding site | 393 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 423 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 453 | Phosphohistidine intermediate | |||
Binding site | 486 | ATP (UniProtKB | ChEBI) | |||
Binding site | 582 | ATP (UniProtKB | ChEBI) | |||
Binding site | 610 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | polyphosphate kinase complex | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | polyphosphate kinase activity | |
Biological Process | phosphorylation | |
Biological Process | polyphosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyphosphate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Aerococcaceae > Aerococcus
Accessions
- Primary accessionA0A178HDU8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Post-translational modification
An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 24-128 | Polyphosphate kinase N-terminal | |||
Domain | 139-321 | Polyphosphate kinase middle | |||
Domain | 350-514 | Polyphosphate kinase C-terminal | |||
Domain | 521-691 | Polyphosphate kinase C-terminal | |||
Sequence similarities
Belongs to the polyphosphate kinase 1 (PPK1) family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length731
- Mass (Da)84,541
- Last updated2016-09-07 v1
- MD5 ChecksumF61D46B93BCC58724D38B48E67359E2C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QMHM01000008 EMBL· GenBank· DDBJ | RAV79455.1 EMBL· GenBank· DDBJ | Genomic DNA |