A0A177ZKC2 · A0A177ZKC2_9BACI
- ProteinMethionine--tRNA ligase
- GenemetG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids544 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Catalytic activity
- tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 141 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 144 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 153 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 156 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 332 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | methionine-tRNA ligase activity | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Lederbergia
Accessions
- Primary accessionA0A177ZKC2
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 4-392 | Methionyl/Leucyl tRNA synthetase | |||
Motif | 10-20 | 'HIGH' region | |||
Motif | 329-333 | 'KMSKS' region | |||
Domain | 432-509 | Methionyl-tRNA synthetase anticodon-binding | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length544
- Mass (Da)62,958
- Last updated2016-09-07 v1
- Checksum877500027A62B2D0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LDJR01000056 EMBL· GenBank· DDBJ | OAK68426.1 EMBL· GenBank· DDBJ | Genomic DNA |