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A0A177AT10 · A0A177AT10_9BILA

  • Protein
    Phosphomannomutase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site10Nucleophile
Binding site10Mg2+ 1 (UniProtKB | ChEBI)
Active site12Proton donor/acceptor
Binding site12Mg2+ 1 (UniProtKB | ChEBI)
Binding site119alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site130alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site137alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site170alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site172alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site201Mg2+ 1 (UniProtKB | ChEBI)
Binding site215Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmetal ion binding
Molecular Functionphosphomannomutase activity
Biological ProcessGDP-mannose biosynthetic process
Biological Processmannose metabolic process
Biological Processprotein N-linked glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomannomutase
  • EC number

Gene names

    • ORF names
      A3Q56_07164

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Intl2013
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Mesozoa > Orthonectida > Rhopaluridae > Intoshia

Accessions

  • Primary accession
    A0A177AT10

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the eukaryotic PMM family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    241
  • Mass (Da)
    27,872
  • Last updated
    2016-09-07 v1
  • MD5 Checksum
    0190C41E50C403918C0711DFD24F7433
MQPNDILVFDLDNTLTFPGEKISKEMNTLINLACKYFTLGIITASSYNNTKRQLVDLHKYQYIFAESGSVFYHNGELIYQKSFCQFVEEEKLQKLINFALKELSNIDLPLKRGNFIEFRKGMINICPIGRNANIEERKIFVHGIRKKLVKKLIKQFGRENFSFLIGGQTSIDVFPSAQNKSLCIDELFQIKRFNNIYFFGDQIKKGEADHQIINDSRINGMPVSCPDDTMVKLKKLLKTVH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LWCA01001434
EMBL· GenBank· DDBJ
OAF65125.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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