A0A177AT10 · A0A177AT10_9BILA
- ProteinPhosphomannomutase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids241 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Catalytic activity
- alpha-D-mannose 1-phosphate = D-mannose 6-phosphate
Cofactor
Pathway
Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 10 | Nucleophile | |||
Binding site | 10 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 12 | Proton donor/acceptor | |||
Binding site | 12 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 119 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 130 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 137 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 170 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 172 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 201 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 215 | Mg2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | metal ion binding | |
Molecular Function | phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process | |
Biological Process | mannose metabolic process | |
Biological Process | protein N-linked glycosylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphomannomutase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mesozoa > Orthonectida > Rhopaluridae > Intoshia
Accessions
- Primary accessionA0A177AT10
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length241
- Mass (Da)27,872
- Last updated2016-09-07 v1
- MD5 Checksum0190C41E50C403918C0711DFD24F7433
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LWCA01001434 EMBL· GenBank· DDBJ | OAF65125.1 EMBL· GenBank· DDBJ | Genomic DNA |