A0A176QEG5 · A0A176QEG5_9MICO

  • Protein
    Pyruvate dehydrogenase E1 component
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site251Mg2+ (UniProtKB | ChEBI)
Binding site281Mg2+ (UniProtKB | ChEBI)
Binding site283Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • ORF names
      AWH69_08830

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CD11-4
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Intrasporangiaceae > Janibacter

Accessions

  • Primary accession
    A0A176QEG5

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain145-315Transketolase N-terminal
Domain503-731Pyruvate dehydrogenase E1 component middle
Domain745-883Transketolase-like C-terminal

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    930
  • Mass (Da)
    104,065
  • Last updated
    2016-09-07 v1
  • Checksum
    97BEBD80613251F1
MTVPDDRPDDGPILNGIPTHLPDIDPDETQEWVESLEALVDQAGRRRARYVMLRLLERARAMNVGVPSLTTTDYVNTIRPEHEPWYPGDEEVERRYRSWIRWNAAVQVHRAQRPEISVGGHISTYASAATLYEVGFNHFWRGKDHPGGGDHIFFQGHASPGMYARAFLEGRLSEDQMDGFRQEKSHEVDGKPFGLPSYPHPRLMPDFWEFPTVSMGLGPMDAIYQAQFNKYLHNRGIKDTSEQHVWAFLGDGEMDEAESRGLLQTAATDELDNLTFVINCNLQRLDGPVRGNGKIIQELEAFFRGAGWNVIKVVWGRGWDPLLAADHDGALVNLMNQTPDGDYQTYRANDGRYVREHFFDRDPRTRKMVQDWSDEDVWWKLKRGGHDYNKVFAAYKAATEHTGQPTVILVKTIKGYGLGTHFAARNATHQMKKLTLDDLKGLRDGLKIPISDEVLEADPKAPPYYHPGTDDEAVRYMLERREKLGGSLPSRRVKYKDLTLPGDDAYKQMAKGSGKQEVATTMAWVRLVKDLMREKDFGDRVVPIIPDEARTFGMDSFFPTKKIYNPHGQNYTSVDADLMLAYKESEQGQIIHTGINEAGSVAAFIAAGSSYATHGQPMIPLYIFYSMFGFQRTGDGIWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSQILAATNPAVVTWDPAFGFEIGHIMRRGLETMYGGDAPQDDPSRNKIYYLTLYNEPYVQPAEPEGVDVDGLLKGMYLYKKGDAEGLGDTPPRCQLLGSGVGMPWVLEAQELLRKDWGVVADAWSVTSWTELRREAMDCDEQAFLHPEQEKRTPYITTALEPAVGPVVAVSDYMKQVQDQIRPWVPEEFSALGTDGFGFSDTRAAARRFFHVDGPSVAVRALQMLAARGWVDASVPEEAAKKYQLLDVRAGTSGNAGGDA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LQZG01000002
EMBL· GenBank· DDBJ
OAB88085.1
EMBL· GenBank· DDBJ
Genomic DNA

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