A0A173DW78 · A0A173DW78_CASFI

  • Protein
    Tripartite motif containing 63 E3 ubiquitin protein ligase
  • Gene
    Trim63
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionubiquitin protein ligase activity
Molecular Functionzinc ion binding
Biological Processprotein ubiquitination

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Tripartite motif containing 63 E3 ubiquitin protein ligase

Gene names

    • Name
      Trim63

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Castorimorpha > Castoridae > Castor

Accessions

  • Primary accession
    A0A173DW78

Subcellular Location

Family & Domains

Features

Showing features for domain, coiled coil, compositional bias, region.

TypeIDPosition(s)Description
Domain23-79RING-type
Domain117-159B box-type
Coiled coil217-266
Domain267-325COS
Compositional bias326-344Acidic residues
Region326-353Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    353
  • Mass (Da)
    40,104
  • Last updated
    2016-09-07 v1
  • Checksum
    8F02B54DC3D7C2AD
MDYKSNLIPDGNPLENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTNRGGSVSMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPMQKGSHLKCKEHEDEKINIYCLTCEVPTCSMCKVFGAHQACEVAPLQSVFQGQKTELSNCISMLVAGNDRVQTIITQLEDSCRMTKENSHHVKEELSQKFDTLYTILDEKKSELLQRITQEQEEKLGFIEALIQQYREQLDKSTKLVETAIQSMDEPGGATFLLSAKQLIKSIVEASKGCQLGKTEQGFENMDYFTLDLQHIAGALRAIDFGTDEDEEEFIEDEEQEEEVSTEGKEEGHQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias326-344Acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KU508521
EMBL· GenBank· DDBJ
ANG60433.1
EMBL· GenBank· DDBJ
mRNA

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