A0A173ADG5 · A0A173ADG5_HUMAN

  • Protein
    HLA class II histocompatibility antigen DQ alpha chain
  • Gene
    HLA-DQA1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendosome membrane
Cellular Componentlysosomal membrane
Cellular ComponentMHC class II protein complex
Biological Processadaptive immune response
Biological Processantigen processing and presentation of peptide or polysaccharide antigen via MHC class II

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • HLA class II histocompatibility antigen DQ alpha chain
    • MHC class I antigen
    • MHC class II antigen
    • MHC class II protein

Gene names

    • Name
      HLA-DQA1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A173ADG5

Organism-specific databases

Subcellular Location

Endosome membrane
; Single-pass type I membrane protein
Lysosome membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane222-240Helical

Keywords

Disease & Variants

Organism-specific databases

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_501505222324-255
Disulfide bond133↔189
Glycosylation144N-acetyl-D-glucosamine
Glycosylation144N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain113-193Ig-like

Sequence similarities

Belongs to the MHC class II family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    255
  • Mass (Da)
    28,000
  • Last updated
    2016-09-07 v1
  • Checksum
    BE0CF3CED76CBAA3
MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYVDLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFIIQGLRSVGASRHQGPL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KU319341
EMBL· GenBank· DDBJ
ANG08756.1
EMBL· GenBank· DDBJ
Genomic DNA
KU319342
EMBL· GenBank· DDBJ
ANG08757.1
EMBL· GenBank· DDBJ
Genomic DNA
KU319343
EMBL· GenBank· DDBJ
ANG08758.1
EMBL· GenBank· DDBJ
Genomic DNA
KU319344
EMBL· GenBank· DDBJ
ANG08759.1
EMBL· GenBank· DDBJ
Genomic DNA
KY057361
EMBL· GenBank· DDBJ
APO40933.1
EMBL· GenBank· DDBJ
Genomic DNA
KY172886
EMBL· GenBank· DDBJ
APO40934.1
EMBL· GenBank· DDBJ
Genomic DNA
LC257816
EMBL· GenBank· DDBJ
BBD34134.1
EMBL· GenBank· DDBJ
Genomic DNA
LC257817
EMBL· GenBank· DDBJ
BBD34135.1
EMBL· GenBank· DDBJ
Genomic DNA
LC257818
EMBL· GenBank· DDBJ
BBD34136.1
EMBL· GenBank· DDBJ
Genomic DNA
LC257819
EMBL· GenBank· DDBJ
BBD34137.1
EMBL· GenBank· DDBJ
Genomic DNA
LC257820
EMBL· GenBank· DDBJ
BBD34138.1
EMBL· GenBank· DDBJ
Genomic DNA
HG993078
EMBL· GenBank· DDBJ
CAE6990116.1
EMBL· GenBank· DDBJ
Genomic DNA
MH892059
EMBL· GenBank· DDBJ
QCF28407.1
EMBL· GenBank· DDBJ
Genomic DNA
MH892064
EMBL· GenBank· DDBJ
QCF28412.1
EMBL· GenBank· DDBJ
Genomic DNA
MK448289
EMBL· GenBank· DDBJ
QCY59244.1
EMBL· GenBank· DDBJ
Genomic DNA
MK610123
EMBL· GenBank· DDBJ
QCY59253.1
EMBL· GenBank· DDBJ
Genomic DNA
MK501650
EMBL· GenBank· DDBJ
QDB65110.1
EMBL· GenBank· DDBJ
Genomic DNA
MK392190
EMBL· GenBank· DDBJ
QEG47625.1
EMBL· GenBank· DDBJ
Genomic DNA
MK392193
EMBL· GenBank· DDBJ
QEG47628.1
EMBL· GenBank· DDBJ
Genomic DNA
MN206022
EMBL· GenBank· DDBJ
QFG58551.1
EMBL· GenBank· DDBJ
Genomic DNA
MN153777
EMBL· GenBank· DDBJ
QFQ66437.1
EMBL· GenBank· DDBJ
Genomic DNA
MN889865
EMBL· GenBank· DDBJ
QHR76760.1
EMBL· GenBank· DDBJ
Genomic DNA
MN889867
EMBL· GenBank· DDBJ
QHR76762.1
EMBL· GenBank· DDBJ
Genomic DNA
MN208443
EMBL· GenBank· DDBJ
QIB00608.1
EMBL· GenBank· DDBJ
Genomic DNA
MN481210
EMBL· GenBank· DDBJ
QJX19982.1
EMBL· GenBank· DDBJ
Genomic DNA
MW344052
EMBL· GenBank· DDBJ
QWV59128.1
EMBL· GenBank· DDBJ
Genomic DNA
MZ171324
EMBL· GenBank· DDBJ
QXL99763.1
EMBL· GenBank· DDBJ
Genomic DNA
MW147020
EMBL· GenBank· DDBJ
QXU63127.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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